pregnant-women-protection

Protection of Pregnant and Breastfeeding Workers Directive, Annex I+II

EU. Chemical Agents: Annexes I & II, Directive 92/85/EEC on Pregnant Workers, 28 November 1992 (updated by table 3 of Annex VI to CLP, 5 October 2018)

This list contains a non-exhaustive inventory of substances to which pregnant workers and workers who have recently given birth or are breastfeeding may not be exposed. Employers are obligated to prevent the exposure of these workers to any agents that may have adverse health effects on either mother or child. The inventory originates from Table 3 of Annex VI to the CLP.

Last updated 19 April 2024. Database contains 2100 unique substances/entries.

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Showing 1 - 100 of 2,100 results.

Substance Name	EC No.	CAS No.	CLP (1272/2008) CMRs	ECCAR Directive 2004/37/EC
(1,3,4,5,6,7-hexahydro-1,3-dioxo-2H-isoindol-2-yl)methyl (1R-trans)-2,2-dimethyl-3-(2-methylprop-1-enyl)cyclopropanecarboxylate	214-619-0	1166-46-7	Carc. 2; STOT SE 2		Details
(1R,2S,5R)-2-[(4-chlorophenyl)methyl]-5-propan-2-yl-1-(1,2,4-triazol-1-ylmethyl)cyclopentan-1-ol	-	115850-69-6	Repr. 1B	yes	Details
(1R,2S,5S)-2-[(4-chlorophenyl)methyl]-5-propan-2-yl-1-(1,2,4-triazol-1-ylmethyl)cyclopentan-1-ol	-	115937-89-8	Repr. 1B	yes	Details
(2-chloroethyl)(3-hydroxypropyl)ammonium chloride CLETOPROPAMINHYDROCHLORID	429-740-6	40722-80-3	Carc. 1B; Muta. 1B	yes	Details
(2-ethylhexanoato-O)(isodecanoato-O)nickel	284-351-7	84852-39-1	Carc. 1A; Muta. 2; Repr. 1B	yes	Details
(2-ethylhexanoato-O)(isononanoato-O)nickel	287-470-2	85508-45-8	Carc. 1A; Muta. 2; Repr. 1B	yes	Details
(2E)-2-cyano-N-[(ethylamino)carbonyl]-2-(methoxyimino) acetamide	-	166900-80-7	Repr. 2		Details
(3,3'-Dimethyl(1,1'-biphenyl)-4,4'-diyl)diammonium bis(hydrogen sulphate)	265-294-7	64969-36-4	Carc. 1B	yes	Details
(3-chloro-2-hydroxypropyl); trimethylammonium chloride ... %	222-048-3	3327-22-8	Carc. 2		Details
(3-chlorophenyl)-(4-methoxy-3-nitrophenyl)methanone T 1569; T001569	423-290-4	66938-41-8	Muta. 2		Details
(4-ethoxyphenyl)(3-(4-fluoro-3-phenoxyphenyl)propyl)dimethylsilane SILANEOPHAN	405-020-7	105024-66-6	Repr. 1B	yes	Details
(4-hydrazinophenyl)-N-methylmethanesulfonamide hydrochloride SULPHAZINE	406-090-1	81880-96-8	Muta. 2		Details
(4-phenylbutyl)phosphinic acid	420-450-5	86552-32-1	Carc. 2		Details
(5-chloro-2-methoxy-4-methyl-3-pyridyl) (4,5,6-trimethoxy-o-tolyl)methanone; pyriofenone	692-456-8	688046-61-9	Carc. 2		Details
(6-(4-hydroxy-3-(2-methoxyphenylazo)-2-sulfonato-7-naphthylamino)-1,3,5-triazin-2,4-diyl)bis[(amino-1-methylethyl)ammonium] formate 2691; CARTASOL BRILLANT SCHARLACH K-2GL KONZ.; CARTASOL BRILLANTSCHARLACH K-2GL FLÜSSIG (ZUBEREITUNG); CARTASOL BRILLANTSCHARLACH K-2GL GRANULAT (ZUBEREITUNG); CARTASOL BRILLIANT SCARLET K-2GL; CARTASOL BRILLIANT SCARLET K-2GL CONC.	402-060-7	108225-03-2	Carc. 1B	yes	Details
(6R-trans)-1-((7-ammonio-2- carboxylato-8-oxo-5-thia-1- azabicyclo-[4.2.0]oct-2-en-3- yl)methyl)pyridinium iodide	423-260-0	100988-63-4	Muta. 2		Details
(E)-2-butenal; (E)-crotonaldehyde	204-647-1	123-73-9	Muta. 2		Details
(E)-3-[1-[4-[2-(dimethylamino)ethoxy]phenyl]-2-phenylbut-1-enyl]phenol CP-166,221	428-010-4	82413-20-5	Carc. 2; Repr. 1B	yes	Details
(isodecanoato-O)(isononanoato-O)nickel	284-348-0	84852-36-8	Carc. 1A; Muta. 2; Repr. 1B	yes	Details
(isodecanoato-O)(isooctanoato-O)nickel	285-909-2	85166-19-4	Carc. 1A; Muta. 2; Repr. 1B	yes	Details
(isononanoato-O)(isooctanoato-O)nickel	287-471-8	85508-46-9	Carc. 1A; Muta. 2; Repr. 1B	yes	Details
(isononanoato-O)(neodecanoato-O)nickel	287-592-6	85551-28-6	Carc. 1A; Muta. 2; Repr. 1B	yes	Details
(isooctanoato-O)(neodecanoato-O)nickel	284-347-5	84852-35-7	Carc. 1A; Muta. 2; Repr. 1B	yes	Details
(methylenebis(4,1-phenylenazo(1-(3-(dimethylamino)propyl)-1,2-dihydro-6-hydroxy-4-methyl-2-oxopyridine-5,3-diyl)))-1,1'dipyridinium dichloride dihydrochloride CARTASOL GEEL M-GL CONC.; CARTASOL GELB M-GL FLÜSSIG (ZUBEREITUNG); CARTASOL GELB M-GL KONZ.; CARTASOL YELLOW M-GL CONC.; HM 2580	401-500-5	118658-99-4	Carc. 1B	yes	Details
(R)-4-hydroxy-3-(3-oxo-1-phenylbutyl)-2-benzopyrone	226-908-9	5543-58-8	Repr. 1A	yes	Details
(R)-5-bromo-3-(1-methyl-2-pyrrolidinyl methyl)-1H-indole UK-111,975	422-390-5	143322-57-0	Repr. 2		Details
(R)-α-phenylethylammonium(-)-(1R, 2S)-(1,2-epoxypropyl)phosphonate monohydrate PHENETHYLAMMONIUM SALT OF FOSFOMYCIN	418-570-8	25383-07-7	Repr. 2		Details
(R, S)-2-amino-3,3-dimethylbutane amide	447-860-7	144177-62-8	Repr. 2		Details
(RS)-1-{1-ethyl-4-[4-mesyl-3-(2-methoxyethoxy)-o-toluoyl]pyrazol-5-yloxy} ethyl methyl carbonate; tolpyralate	701-225-3	1101132-67-5	Carc. 2; Repr. 2		Details
(RS)-4-[1-(2,3-dimethylphenyl)ethyl]-1H-imidazole; medetomidine	811-718-6	86347-14-0	STOT SE 1		Details
(S)-2,3-dihydro-1H-indole-2-carboxylic acid [S]-2-INDOLINE CARBOXYLIC ACID	410-860-2	79815-20-6	Repr. 2		Details
(S)-4-hydroxy-3-(3-oxo-1-phenylbutyl)-2-benzopyrone	226-907-3	5543-57-7	Repr. 1A	yes	Details
(Z)-2-methoxymino-2-[2-(tritylamino)thiazol-4-yl]acetic acid	431-520-1	64485-90-1	Carc. 2		Details
1,1,2-trichloroethane	201-166-9	79-00-5	Carc. 2		Details
1,1-dichloroethylene; vinylidene chloride	200-864-0	75-35-4	Carc. 2		Details
1,2,3,4,5,6-hexachlorcyclohexanes with the exception of those specified elsewhere in this Annex	210-168-9	608-73-1	Carc. 2		Details
1,2,3-trichloropropane	202-486-1	96-18-4	Carc. 1B; Repr. 1B	yes	Details
1,2,4-triazole	206-022-9	288-88-0	Repr. 1B	yes	Details
1,2,5,6,9,10-hexabromocyclododecane	221-695-9	3194-55-6	Repr. 2		Details
1,2-benzenedicarboxylic acid, dihexyl ester, branched and linear	271-093-5	68515-50-4	Repr. 1B	yes	Details
1,2-benzenedicarboxylic acid, dipentylester, branched and linear	284-032-2	84777-06-0	Repr. 1B	yes	Details
1,2-benzenedicarboxylic acid; di-C6-8-branched alkylesters, C7-rich	276-158-1	71888-89-6	Repr. 1B	yes	Details
1,2-benzenedicarboxylic acid; di-C7-11-branched and linear alkylesters	271-084-6	68515-42-4	Repr. 1B	yes	Details
1,2-bis(2-methoxyethoxy)ethane; TEGDME; triethylene glycol dimethyl ether; triglyme	203-977-3	112-49-2	Repr. 1B	yes	Details
1,2-dibromo-3-chloropropane	202-479-3	96-12-8	Carc. 1B; Muta. 1B; Repr. 1A	yes	Details
1,2-dibromoethane	203-444-5	106-93-4	Carc. 1B	yes	Details
1,2-dichloroethane; ethylene dichloride	203-458-1	107-06-2	Carc. 1B	yes	Details
1,2-dichloropropane; propylene dichloride	201-152-2	78-87-5	Carc. 1B	yes	Details
1,2-diethoxyethane	211-076-1	629-14-1	Repr. 1A	yes	Details
1,2-dihydroxybenzene; pyrocatechol	204-427-5	120-80-9	Carc. 1B; Muta. 2	yes	Details
1,2-dimethoxyethane; ethylene glycol dimethyl ether; EGDME	203-794-9	110-71-4	Repr. 1B	yes	Details
1,2-dimethylhydrazine	-	540-73-8	Carc. 1B	yes	Details
1,2-epoxybutane	203-438-2	106-88-7	Carc. 2		Details
1,3,5-triazine-2,4,6-triamine; melamine	203-615-4	108-78-1	Carc. 2		Details
1,3,5-trioxan; trioxymethylene	203-812-5	110-88-3	Repr. 2		Details
1,3,5-tris(oxiranylmethyl)-1,3,5-triazine-2,4,6(1H,3H,5H)-trione; TGIC	219-514-3	2451-62-9	Muta. 1B	yes	Details
1,3,5-tris-[(2S and 2R)-2,3-epoxypropyl]-1,3,5-triazine-2,4,6-(1H,3H,5H)-trione TEPIC-H	423-400-0	59653-74-6	Muta. 1B	yes	Details
1,3-bis(vinylsulfonylacetamido)propane H-604	428-350-3	93629-90-4	Muta. 2		Details
1,3-butadiene; buta-1,3-diene	203-450-8	106-99-0	Carc. 1A; Muta. 1B	yes	Details
1,3-dichloro-2-propanol	202-491-9	96-23-1	Carc. 1B	yes	Details
1,3-diphenylguanidine	203-002-1	102-06-7	Repr. 2		Details
1,3-propanesultone; 1,2-oxathiolane 2,2-dioxide	214-317-9	1120-71-4	Carc. 1B	yes	Details
1,4,5,8-tetraaminoanthra; quinone; C.I. Disperse Blue 1	219-603-7	2475-45-8	Carc. 1B	yes	Details
1,4-Benzenediamine, N,N'-mixed Ph and tolyl derivs.	273-227-8	68953-84-4	Repr. 1B	yes	Details
1,4-dichlorobenzene; p-dichlorobenzene	203-400-5	106-46-7	Carc. 2		Details
1,4-dichlorobut-2-ene	212-121-8	764-41-0	Carc. 1B	yes	Details
1,4-dihydroxybenzene; hydroquinone; quinol	204-617-8	123-31-9	Carc. 2; Muta. 2		Details
1,4-dioxane	204-661-8	123-91-1	Carc. 1B	yes	Details
1,5-naphthylenediamine	218-817-8	2243-62-1	Carc. 2		Details
1-(1-naphthylmethyl)quinolinium chloride CIB R634	406-220-7	65322-65-8	Carc. 2; Muta. 2		Details
1-(2-amino-5-chlorophenyl)-2,2,2-trifluoro-1,1-ethanediol, hydrochloride [containing ≥ 0,1 % 4-chloroaniline (EC No 203-401-0)]	433-580-2	214353-17-0	Carc. 1B	yes	Details
1-bromo-2-methylpropyl propionate	422-900-6	158894-67-8	Carc. 2		Details
1-bromo-3,4,5-trifluorobenzene 1-BROM-3,4,5-TRIFLUORBENZOL; 1-BROMO-3,4,5-TRIFLUOROBENZENE	418-480-9	138526-69-9	Carc. 2		Details
1-bromopropane; n-propyl bromide	203-445-0	106-94-5	Repr. 1B	yes	Details
1-chloro-2,3-epoxypropane; epichlorhydrin	203-439-8	106-89-8	Carc. 1B	yes	Details
1-chloro-4-nitrobenzene	202-809-6	100-00-5	Carc. 2; Muta. 2		Details
1-cyclopropyl-6,7-difluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic acid CHINOLONCARBONSÄURE 93-073; CP-70,335	413-760-7	93107-30-3	Repr. 2		Details
1-ethyl-1-methylmorpholinium bromide MEM	418-250-8	65756-41-4	Muta. 2		Details
1-ethyl-1-methylpyrrolidinium bromide MEP	418-200-5	69227-51-6	Muta. 2		Details
1-methyl-3-nitro-1-nitrosoguanidine	200-730-1	70-25-7	Carc. 1B	yes	Details
1-vinyl-2-pyrrolidone	201-800-4	88-12-0	Carc. 2		Details
1-vinylimidazole	214-012-0	1072-63-5	Repr. 1B	yes	Details
2,2',6,6'-tetrabromo-4,4'-isopropylidenediphenol; tetrabromobisphenol-A	201-236-9	79-94-7	Carc. 1B	yes	Details
2,2'-((3,3', 5,5'-tetramethyl-(1,1'-biphenyl)-4,4'-diyl)-bis(oxymethylene))-bis-oxirane EPIKOTE YX4000; EPIKOTE YX4000H; YX-4000	413-900-7	85954-11-6	Carc. 2		Details
2,2'-(nitrosoimino)bisethanol	214-237-4	1116-54-7	Carc. 1B	yes	Details
2,2'-bioxirane; 1,2:3,4-diepoxybutane	215-979-1	1464-53-5	Carc. 1B; Muta. 1B	yes	Details
2,2'-dichloro-4,4'-methylenedianiline; 4,4'-methylene bis(2-chloroaniline)	202-918-9	101-14-4	Carc. 1B	yes	Details
2,2'-methylenediphenyl diisocyanate; diphenylmethane-2,2'-diisocyanate	219-799-4	2536-05-2	Carc. 2		Details
2,2-bis(bromomethyl)propane-1,3-diol	221-967-7	3296-90-0	Carc. 1B; Muta. 1B	yes	Details
2,2-dibromo-2-nitroethanol PERMACHEM N21	412-380-9	69094-18-4	Carc. 2		Details
2,2-dimethylpropan-1-ol, tribromo derivative	253-057-0	36483-57-5	Carc. 1B; Muta. 2	yes	Details
2,3,4-trichlorobut-1-ene	219-397-9	2431-50-7	Carc. 2		Details
2,3,5,6-tetrafluoro-4-(methoxymethyl)benzyl (1R,3R)-2,2-dimethyl-3-[(1Z)-prop-1-en-1-yl]cyclopropanecarboxylate; epsilon-metofluthrin	-	240494-71-7	STOT SE 1		Details
2,3,5,6-tetrafluoro-4-(methoxymethyl)benzyl (Z)-(1R,3R)-3-(2-cyanoprop-1-enyl)-2,2-dimethylcyclopropanecarboxylate; epsilon-momfluorothrin	-	1065124-65-3	STOT SE 2		Details
2,3-dibromopropan-1-ol; 2,3-dibromo-1-propanol	202-480-9	96-13-9	Carc. 1B; Repr. 2	yes	Details
2,3-dichloropropene; 2,3-dichloropropylene	201-153-8	78-88-6	Muta. 2		Details
2,3-dinitrotoluene	210-013-5	602-01-7	Carc. 1B; Muta. 2; Repr. 2	yes	Details
2,3-epoxypropan-1-ol; glycidol; oxiranemethanol	209-128-3	556-52-5	Carc. 1B; Muta. 2; Repr. 1B	yes	Details
2,3-epoxypropyl methacrylate; glycidyl methacrylate	203-441-9	106-91-2	Carc. 1B; Muta. 2; Repr. 1B	yes	Details
2,3-epoxypropyl o-tolyl ether	218-645-3	2210-79-9	Muta. 2		Details

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pregnant-women-protection

pregnant-women-protection

Protection of Pregnant and Breastfeeding Workers Directive, Annex I+II

EU. Chemical Agents: Annexes I & II, Directive 92/85/EEC on Pregnant Workers, 28 November 1992 (updated by table 3 of Annex VI to CLP, 5 October 2018)

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Last updated 19 April 2024. Database contains 2100 unique substances/entries.

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