pregnant-women-protection

Protection of Pregnant and Breastfeeding Workers Directive, Annex I+II

EU. Chemical Agents: Annexes I & II, Directive 92/85/EEC on Pregnant Workers, 28 November 1992 (updated by table 3 of Annex VI to CLP, 5 October 2018)

This list contains a non-exhaustive inventory of substances to which pregnant workers and workers who have recently given birth or are breastfeeding may not be exposed. Employers are obligated to prevent the exposure of these workers to any agents that may have adverse health effects on either mother or child. The inventory originates from Table 3 of Annex VI to the CLP.

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Last updated 25 April 2024. Database contains 2100 unique substances/entries.
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Substance Name
EC No.
CAS No.
CLP (1272/2008) CMRs
ECCAR Directive 2004/37/EC
 
2,3-epoxypropyl o-tolyl ether
218-645-3
2210-79-9
Muta. 2
Details
2,3-epoxypropyl methacrylate; glycidyl methacrylate
203-441-9
106-91-2
Carc. 1B; Muta. 2; Repr. 1B
yes
 Details
2,3-epoxypropan-1-ol; glycidol; oxiranemethanol
209-128-3
556-52-5
Carc. 1B; Muta. 2; Repr. 1B
yes
 Details
2,3-dinitrotoluene
210-013-5
602-01-7
Carc. 1B; Muta. 2; Repr. 2
yes
 Details
2,3-dichloropropene; 2,3-dichloropropylene
201-153-8
78-88-6
Muta. 2
Details
2,3-dibromopropan-1-ol; 2,3-dibromo-1-propanol
202-480-9
96-13-9
Carc. 1B; Repr. 2
yes
 Details
2,3,5,6-tetrafluoro-4-(methoxymethyl)benzyl (Z)-(1R,3R)-3-(2-cyanoprop-1-enyl)-2,2-dimethylcyclopropanecarboxylate; epsilon-momfluorothrin
-
1065124-65-3
STOT SE 2
Details
2,3,5,6-tetrafluoro-4-(methoxymethyl)benzyl (1R,3R)-2,2-dimethyl-3-[(1Z)-prop-1-en-1-yl]cyclopropanecarboxylate; epsilon-metofluthrin
-
240494-71-7
STOT SE 1
Details
2,3,4-trichlorobut-1-ene
219-397-9
2431-50-7
Carc. 2
Details
2,2-dimethylpropan-1-ol, tribromo derivative
253-057-0
36483-57-5
Carc. 1B; Muta. 2
yes
 Details
2,2-dibromo-2-nitroethanol
PERMACHEM N21
412-380-9
69094-18-4
Carc. 2
Details
2,2-bis(bromomethyl)propane-1,3-diol
221-967-7
3296-90-0
Carc. 1B; Muta. 1B
yes
 Details
2,2'-methylenediphenyl diisocyanate; diphenylmethane-2,2'-diisocyanate
219-799-4
2536-05-2
Carc. 2
Details
2,2'-dichloro-4,4'-methylenedianiline; 4,4'-methylene bis(2-chloroaniline)
202-918-9
101-14-4
Carc. 1B
yes
 Details
2,2'-bioxirane; 1,2:3,4-diepoxybutane
215-979-1
1464-53-5
Carc. 1B; Muta. 1B
yes
 Details
2,2'-(nitrosoimino)bisethanol
214-237-4
1116-54-7
Carc. 1B
yes
 Details
2,2'-((3,3', 5,5'-tetramethyl-(1,1'-biphenyl)-4,4'-diyl)-bis(oxymethylene))-bis-oxirane
EPIKOTE YX4000; EPIKOTE YX4000H; YX-4000
413-900-7
85954-11-6
Carc. 2
Details
2,2',6,6'-tetrabromo-4,4'-isopropylidenediphenol; tetrabromobisphenol-A
201-236-9
79-94-7
Carc. 1B
yes
 Details
1-vinylimidazole
214-012-0
1072-63-5
Repr. 1B
yes
 Details
1-vinyl-2-pyrrolidone
201-800-4
88-12-0
Carc. 2
Details
1-methyl-3-nitro-1-nitrosoguanidine
200-730-1
70-25-7
Carc. 1B
yes
 Details
1-ethyl-1-methylpyrrolidinium bromide
MEP
418-200-5
69227-51-6
Muta. 2
Details
1-ethyl-1-methylmorpholinium bromide
MEM
418-250-8
65756-41-4
Muta. 2
Details
1-cyclopropyl-6,7-difluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic acid
CHINOLONCARBONSÄURE 93-073; CP-70,335
413-760-7
93107-30-3
Repr. 2
Details
1-chloro-4-nitrobenzene
202-809-6
100-00-5
Carc. 2; Muta. 2
Details
1-chloro-2,3-epoxypropane; epichlorhydrin
203-439-8
106-89-8
Carc. 1B
yes
 Details
1-bromopropane; n-propyl bromide
203-445-0
106-94-5
Repr. 1B
yes
 Details
1-bromo-3,4,5-trifluorobenzene
1-BROM-3,4,5-TRIFLUORBENZOL; 1-BROMO-3,4,5-TRIFLUOROBENZENE
418-480-9
138526-69-9
Carc. 2
Details
1-bromo-2-methylpropyl propionate
422-900-6
158894-67-8
Carc. 2
Details
1-(2-amino-5-chlorophenyl)-2,2,2-trifluoro-1,1-ethanediol, hydrochloride [containing ≥ 0,1 % 4-chloroaniline (EC No 203-401-0)]
433-580-2
214353-17-0
Carc. 1B
yes
 Details
1-(1-naphthylmethyl)quinolinium chloride
CIB R634
406-220-7
65322-65-8
Carc. 2; Muta. 2
Details
1,5-naphthylenediamine
218-817-8
2243-62-1
Carc. 2
Details
1,4-dioxane
204-661-8
123-91-1
Carc. 1B
yes
 Details
1,4-dihydroxybenzene; hydroquinone; quinol
204-617-8
123-31-9
Carc. 2; Muta. 2
Details
1,4-dichlorobut-2-ene
212-121-8
764-41-0
Carc. 1B
yes
 Details
1,4-dichlorobenzene; p-dichlorobenzene
203-400-5
106-46-7
Carc. 2
Details
1,4-Benzenediamine, N,N'-mixed Ph and tolyl derivs.
273-227-8
68953-84-4
Repr. 1B
yes
 Details
1,4,5,8-tetraaminoanthra; quinone; C.I. Disperse Blue 1
219-603-7
2475-45-8
Carc. 1B
yes
 Details
1,3-propanesultone; 1,2-oxathiolane 2,2-dioxide
214-317-9
1120-71-4
Carc. 1B
yes
 Details
1,3-diphenylguanidine
203-002-1
102-06-7
Repr. 2
Details
1,3-dichloro-2-propanol
202-491-9
96-23-1
Carc. 1B
yes
 Details
1,3-butadiene; buta-1,3-diene
203-450-8
106-99-0
Carc. 1A; Muta. 1B
yes
 Details
1,3-bis(vinylsulfonylacetamido)propane
H-604
428-350-3
93629-90-4
Muta. 2
Details
1,3,5-tris-[(2S and 2R)-2,3-epoxypropyl]-1,3,5-triazine-2,4,6-(1H,3H,5H)-trione
TEPIC-H
423-400-0
59653-74-6
Muta. 1B
yes
 Details
1,3,5-tris(oxiranylmethyl)-1,3,5-triazine-2,4,6(1H,3H,5H)-trione; TGIC
219-514-3
2451-62-9
Muta. 1B
yes
 Details
1,3,5-trioxan; trioxymethylene
203-812-5
110-88-3
Repr. 2
Details
1,3,5-triazine-2,4,6-triamine; melamine
203-615-4
108-78-1
Carc. 2
Details
1,2-epoxybutane
203-438-2
106-88-7
Carc. 2
Details
1,2-dimethylhydrazine
-
540-73-8
Carc. 1B
yes
 Details
1,2-dimethoxyethane; ethylene glycol dimethyl ether; EGDME
203-794-9
110-71-4
Repr. 1B
yes
 Details
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