pregnant-women-protection

Protection of Pregnant and Breastfeeding Workers Directive, Annex I+II

EU. Chemical Agents: Annexes I & II, Directive 92/85/EEC on Pregnant Workers, 28 November 1992 (updated by table 3 of Annex VI to CLP, 5 October 2018)

This list contains a non-exhaustive inventory of substances to which pregnant workers and workers who have recently given birth or are breastfeeding may not be exposed. Employers are obligated to prevent the exposure of these workers to any agents that may have adverse health effects on either mother or child. The inventory originates from Table 3 of Annex VI to the CLP.

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Last updated 25 April 2024. Database contains 2100 unique substances/entries.
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Substance Name
EC No.
CAS No.
CLP (1272/2008) CMRs
ECCAR Directive 2004/37/EC
 
(E)-2-butenal; (E)-crotonaldehyde
204-647-1
123-73-9
Muta. 2
Details
(R)-5-bromo-3-(1-methyl-2-pyrrolidinyl methyl)-1H-indole
UK-111,975
422-390-5
143322-57-0
Repr. 2
Details
(R)-α-phenylethylammonium(-)-(1R, 2S)-(1,2-epoxypropyl)phosphonate monohydrate
PHENETHYLAMMONIUM SALT OF FOSFOMYCIN
418-570-8
25383-07-7
Repr. 2
Details
(R, S)-2-amino-3,3-dimethylbutane amide
447-860-7
144177-62-8
Repr. 2
Details
(RS)-1-{1-ethyl-4-[4-mesyl-3-(2-methoxyethoxy)-o-toluoyl]pyrazol-5-yloxy} ethyl methyl carbonate; tolpyralate
701-225-3
1101132-67-5
Carc. 2; Repr. 2
Details
(RS)-4-[1-(2,3-dimethylphenyl)ethyl]-1H-imidazole; medetomidine
811-718-6
86347-14-0
STOT SE 1
Details
(S)-2,3-dihydro-1H-indole-2-carboxylic acid
[S]-2-INDOLINE CARBOXYLIC ACID
410-860-2
79815-20-6
Repr. 2
Details
(Z)-2-methoxymino-2-[2-(tritylamino)thiazol-4-yl]acetic acid
431-520-1
64485-90-1
Carc. 2
Details
1,1,2-trichloroethane
201-166-9
79-00-5
Carc. 2
Details
1,1-dichloroethylene; vinylidene chloride
200-864-0
75-35-4
Carc. 2
Details
1,2,3,4,5,6-hexachlorcyclohexanes with the exception of those specified elsewhere in this Annex
210-168-9
608-73-1
Carc. 2
Details
1,2,5,6,9,10-hexabromocyclododecane
221-695-9
3194-55-6
Repr. 2
Details
1,2-epoxybutane
203-438-2
106-88-7
Carc. 2
Details
1,3,5-triazine-2,4,6-triamine; melamine
203-615-4
108-78-1
Carc. 2
Details
1,3,5-trioxan; trioxymethylene
203-812-5
110-88-3
Repr. 2
Details
1,3-bis(vinylsulfonylacetamido)propane
H-604
428-350-3
93629-90-4
Muta. 2
Details
1,3-diphenylguanidine
203-002-1
102-06-7
Repr. 2
Details
1,4-dichlorobenzene; p-dichlorobenzene
203-400-5
106-46-7
Carc. 2
Details
1,4-dihydroxybenzene; hydroquinone; quinol
204-617-8
123-31-9
Carc. 2; Muta. 2
Details
1,5-naphthylenediamine
218-817-8
2243-62-1
Carc. 2
Details
1-(1-naphthylmethyl)quinolinium chloride
CIB R634
406-220-7
65322-65-8
Carc. 2; Muta. 2
Details
1-bromo-2-methylpropyl propionate
422-900-6
158894-67-8
Carc. 2
Details
1-bromo-3,4,5-trifluorobenzene
1-BROM-3,4,5-TRIFLUORBENZOL; 1-BROMO-3,4,5-TRIFLUOROBENZENE
418-480-9
138526-69-9
Carc. 2
Details
1-chloro-4-nitrobenzene
202-809-6
100-00-5
Carc. 2; Muta. 2
Details
1-cyclopropyl-6,7-difluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic acid
CHINOLONCARBONSÄURE 93-073; CP-70,335
413-760-7
93107-30-3
Repr. 2
Details
1-ethyl-1-methylmorpholinium bromide
MEM
418-250-8
65756-41-4
Muta. 2
Details
1-ethyl-1-methylpyrrolidinium bromide
MEP
418-200-5
69227-51-6
Muta. 2
Details
1-vinyl-2-pyrrolidone
201-800-4
88-12-0
Carc. 2
Details
2,2'-((3,3', 5,5'-tetramethyl-(1,1'-biphenyl)-4,4'-diyl)-bis(oxymethylene))-bis-oxirane
EPIKOTE YX4000; EPIKOTE YX4000H; YX-4000
413-900-7
85954-11-6
Carc. 2
Details
2,2'-methylenediphenyl diisocyanate; diphenylmethane-2,2'-diisocyanate
219-799-4
2536-05-2
Carc. 2
Details
2,2-dibromo-2-nitroethanol
PERMACHEM N21
412-380-9
69094-18-4
Carc. 2
Details
2,3,4-trichlorobut-1-ene
219-397-9
2431-50-7
Carc. 2
Details
2,3,5,6-tetrafluoro-4-(methoxymethyl)benzyl (1R,3R)-2,2-dimethyl-3-[(1Z)-prop-1-en-1-yl]cyclopropanecarboxylate; epsilon-metofluthrin
-
240494-71-7
STOT SE 1
Details
2,3,5,6-tetrafluoro-4-(methoxymethyl)benzyl (Z)-(1R,3R)-3-(2-cyanoprop-1-enyl)-2,2-dimethylcyclopropanecarboxylate; epsilon-momfluorothrin
-
1065124-65-3
STOT SE 2
Details
2,3-dichloropropene; 2,3-dichloropropylene
201-153-8
78-88-6
Muta. 2
Details
2,3-epoxypropyl o-tolyl ether
218-645-3
2210-79-9
Muta. 2
Details
2,4,6,8-tetramethyl-1,3,5,7-tetraoxacyclooctane; metaldehyde
203-600-2
108-62-3
Repr. 2
Details
2,4,6-trichlorophenol
201-795-9
88-06-2
Carc. 2
Details
2,6-xylidine; 2,6-dimethylaniline
201-758-7
87-62-7
Carc. 2
Details
2-(2-hydroxy-3,5-dinitroanilino)ethanol
PIKRAMINROT
412-520-9
99610-72-7
Repr. 2
Details
2-(4-tert-butylphenyl)ethanol
TBPE
410-020-5
5406-86-0
Repr. 2
Details
2-(isocyanatosulfonylmethyl)benzoic acid methyl ester; (alt.):methyl 2-(isocyanatosulfonylmethyl)benzoate
MCPSI
410-900-9
83056-32-0
Muta. 2
Details
2-aminophenol
202-431-1
95-55-6
Muta. 2
Details
2-chloracetamide
201-174-2
79-07-2
Repr. 2
Details
2-ethyl-2-[[(1-oxoallyl)oxy]methyl]-1,3-propanediyl diacrylate; 2,2-bis(acryloyloxymethyl)butyl acrylate; trimethylolpropane triacrylate
239-701-3
15625-89-5
Carc. 2
Details
2-ethylhexyl 10-ethyl-4,4-dimethyl-7-oxo-8-oxa-3,5-dithia-4-stannatetradecanoate
260-829-0
57583-35-4
Repr. 2
Details
2-ethylhexyl 10-ethyl-4-[[2-[(2-ethylhexyl)oxy]-2-oxoethyl]thio]-4-methyl-7-oxo-8-oxa-3,5-dithia-4-stannatetradecanoate
260-828-5
57583-34-3
Repr. 2
Details
2-ethylhexyl-2-ethylhexanoate
231-057-1
7425-14-1
Repr. 2
Details
2-ethylphenylhydrazine hydrochloride
2-EPH
421-460-2
19398-06-2
Carc. 2
Details
2-furaldehyde
202-627-7
98-01-1
Carc. 2
Details
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