pregnant-women-protection

Protection of Pregnant and Breastfeeding Workers Directive, Annex I+II

EU. Chemical Agents: Annexes I & II, Directive 92/85/EEC on Pregnant Workers, 28 November 1992 (updated by table 3 of Annex VI to CLP, 5 October 2018)

This list contains a non-exhaustive inventory of substances to which pregnant workers and workers who have recently given birth or are breastfeeding may not be exposed. Employers are obligated to prevent the exposure of these workers to any agents that may have adverse health effects on either mother or child. The inventory originates from Table 3 of Annex VI to the CLP.

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Last updated 26 April 2024. Database contains 2100 unique substances/entries.
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Substance Name
EC No.
CAS No.
CLP (1272/2008) CMRs
ECCAR Directive 2004/37/EC
 
epoxiconazole (ISO); (2RS,3SR)-3-(2-chlorophenyl)-2-(4-fluorophenyl)-[(1H-1,2,4-triazol-1-yl)methyl]oxirane
406-850-2
133855-98-8
Carc. 2; Repr. 1B
yes
 Details
diethanolamine perfluorooctane sulfonate
274-460-8
70225-14-8
Carc. 2; Repr. 1B
yes
 Details
carbetamide (ISO); (R)-1-(ethylcarbamoyl) ethyl carbanilate; (2R)-1-(ethylamino)-1-oxopropan-2-yl phenylcarbamate
240-286-6
16118-49-3
Carc. 2; Repr. 1B
yes
 Details
ammoniumpentadeca-fluorooctanoate
223-320-4
3825-26-1
Carc. 2; Repr. 1B
yes
 Details
Ammonium salts of perfluorononan-1-oic-acid
-
4149-60-4
Carc. 2; Repr. 1B
yes
 Details
ammonium perfluorooctanesulfonate; ammonium heptadecafluorooctanesulfonate
249-415-0
29081-56-9
Carc. 2; Repr. 1B
yes
 Details
ammonium nonadecafluorodecanoate
221-470-5
3108-42-7
Carc. 2; Repr. 1B
yes
 Details
(E)-3-[1-[4-[2-(dimethylamino)ethoxy]phenyl]-2-phenylbut-1-enyl]phenol
CP-166,221
428-010-4
82413-20-5
Carc. 2; Repr. 1B
yes
 Details
methylmercuric chloride
204-064-2
115-09-3
Carc. 2; Repr. 1A
yes
 Details
lead acetate, basic
215-630-3
1335-32-6
Carc. 2; Repr. 1A
yes
 Details
allyl glycidyl ether; allyl 2,3-epoxypropyl ether; prop-2-en-1-yl 2,3-epoxypropyl ether
203-442-4
106-92-3
Carc. 2; Muta. 2; Repr. 2
Details
thiophanate-methyl (ISO); dimethyl (1,2-phenylenedicarbamothioyl)biscarbamate; dimethyl 4,4'-(o-phenylene) bis(3-thioallophanate)
245-740-7
23564-05-8
Carc. 2; Muta. 2
Details
salts of aniline
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Benzenesulfonic acid, 2,2'-dithiobis(5-methyl-, compd. with benzenamine (1:2) EC / List no: - | CAS no: 63468-80-4
Anilinium p-tolylsulphonate EC / List no: 237-870-8 | CAS no: 14034-57-2
Aniline EC / List no: 200-539-3 | CAS no: 62-53-3
Anilinium dihydrogen phosphate EC / List no: 253-680-8 | CAS no: 37832-42-1
Anilinium chloride EC / List no: 205-519-8 | CAS no: 142-04-1
Phthalic acid, compound with aniline (1:1) EC / List no: 256-856-2 | CAS no: 50930-79-5
Anilinium bromide EC / List no: 208-801-9 | CAS no: 542-11-0
Dianilinium sulphate EC / List no: 208-805-0 | CAS no: 542-16-5
Benzenesulfonic acid, 2(or 4)-methyl-, compd. with benzenamine (1:1) EC / List no: - | CAS no: 70788-38-4
Anilinium acetate EC / List no: 208-802-4 | CAS no: 542-14-3
Anilinetrifluoroboron EC / List no: 211-539-8 | CAS no: 660-53-7
-
-
Carc. 2; Muta. 2
Details
o-phenylenediamine dihydrochloride
210-418-7
615-28-1
Carc. 2; Muta. 2
Details
o-phenylenediamine
202-430-6
95-54-5
Carc. 2; Muta. 2
Details
leucomalachite green; N, N,N',N'-tetramethyl-4,4'-benzylidenedianiline
204-961-9
129-73-7
Carc. 2; Muta. 2
Details
C.I. Solvent Yellow 14; 1-phenylazo-2-naphthol
212-668-2
842-07-9
Carc. 2; Muta. 2
Details
butyl glycidyl ether; butyl 2,3-epoxypropyl ether
219-376-4
2426-08-6
Carc. 2; Muta. 2
Details
Aniline
200-539-3
62-53-3
Carc. 2; Muta. 2
Details
3-chloropropene; allyl chloride
203-457-6
107-05-1
Carc. 2; Muta. 2
Details
1-chloro-4-nitrobenzene
202-809-6
100-00-5
Carc. 2; Muta. 2
Details
1-(1-naphthylmethyl)quinolinium chloride
CIB R634
406-220-7
65322-65-8
Carc. 2; Muta. 2
Details
1,4-dihydroxybenzene; hydroquinone; quinol
204-617-8
123-31-9
Carc. 2; Muta. 2
Details
α, α-dichlorotoluene; benzylidene chloride; benzal chloride
202-709-2
98-87-3
Carc. 2
Details
vinyl acetate
203-545-4
108-05-4
Carc. 2
Details
UVCB condensation product of: tetrakis-hydroxymethylphosphonium chloride, urea and distilled hydrogenated C16-18 tallow alkylamine
ITC 826 CONCENTRATE
422-720-8
166242-53-1
Carc. 2
Details
trisodium nitrilotriacetate
225-768-6
5064-31-3
Carc. 2
Details
tris[2-chloro-1-(chloromethyl)ethyl] phosphate
237-159-2
13674-87-8
Carc. 2
Details
triflusulfuron-methyl; methyl 2-({[4-(dimethylamino)-6- (2,2,2-trifluoroethoxy)-1,3,5- triazin-2-yl]carbamoyl}sulfamoyl)-3-methylbenzoate
603-146-9
126535-15-7
Carc. 2
Details
trifluralin (ISO) (containing <0.5 ppm NPDA); α, α, α-trifluoro-2,6-dinitro-N, N-dipropyl-p-toluidine (containing; < 0,5 ppm NPDA); 2,6-dinitro-N, N-dipropyl-4-trifluoromethylaniline (containing < 0,5 ppm NPDA); N, N-dipropyl-2,6-dinitro-4-trifluoromethylaniline (containing < 0.5 ppm NPDA)
216-428-8
1582-09-8
Carc. 2
Details
tributyl phosphate
204-800-2
126-73-8
Carc. 2
Details
tralkoxydim (ISO); 2-(N-ethoxypropanimidoyl)-3-hydroxy-5-mesitylcyclohex-2-en-1-one
618-075-9
87820-88-0
Carc. 2
Details
toluidinium chloride
208-740-8
540-23-8
Carc. 2
Details
toluidine sulphate (1:1)
208-741-3
540-25-0
Carc. 2
Details
titanium dioxide [in powder form containing 1 % or more of particles with aerodynamic diameter ≤ 10 μm]
236-675-5
13463-67-7
Carc. 2
Details
tetrahydrofuran
203-726-8
109-99-9
Carc. 2
Details
tetrachloroethylene
204-825-9
127-18-4
Carc. 2
Details
sodiumpentachlorophenolate
205-025-2
131-52-2
Carc. 2
Details
simazine (ISO); 6-chloro-N,N'-diethyl-1,3,5-triazine-2,4-diamine
204-535-2
122-34-9
Carc. 2
Details
salts of 4,4'-carbonimidoylbis[N, N-dimethylaniline]
show/hide
4,4'-carbonimidoylbis[N,N-dimethylanilinium] sulphate EC / List no: 282-562-9 | CAS no: 84255-16-3
Benzenamine, 4,4'-carbonimidoylbis[N,N-dimethyl-, monohydrochloride, 2-hydroxyethanesulfonate EC / List no: - | CAS no: 86157-51-9
Methanaminium, N-(4-(amino(4-(dimethylamino)phenyl)methylene)-2,5-cyclohexadien-1-ylidene)-N-methyl-, dodecyl(sulfophenoxy)benzenesulfonate (2:1) EC / List no: - | CAS no: 63428-09-1
4,4'-carbonimidoylbis(N,N-dimethylaniline) monohydrochloride EC / List no: 219-567-2 | CAS no: 2465-27-2
4,4'-carbonimidoylbis[N,N-dimethylaniline] acetate EC / List no: 225-801-4 | CAS no: 5089-20-3
Benzenesulfonic acid, 4-dodecyl-, compd. with 4,4'-carbonimidoylbis(N,N-dimethylbenzenamine) (1:1) EC / List no: - | CAS no: 63589-43-5
Decyl hydrogen sulphate, compound with 4,4'-carbonimidoylbis[N,N-dimethylaniline] (1:1) EC / List no: 281-828-1 | CAS no: 84030-53-5
Benzenamine, 4,4'-carbonimidoylbis[N,N-dimethyl-, mono(dodecylbenzenesulfonate) EC / List no: - | CAS no: 82794-01-2
4,4'-carbonimidoylbis[N,N-dimethylaniline] nitrate EC / List no: 282-561-3 | CAS no: 84255-15-2
4,4'-bis[(4,5-dihydro-3-methyl-5-oxo-1-phenyl-1H-pyrazol-4-yl)azo][1,1'-biphenyl]-2,2'-disulphonic acid, compound with 4,4'-carbonimidoylbis[N,N-dimethylphenylamine] (1:2) EC / List no: 277-106-0 | CAS no: 72939-51-6
Benzenamine, 4,4'-carbonimidoylbis[N,N-dimethyl-, monohydrochloride, (2-methoxyethoxy)acetate EC / List no: - | CAS no: 82941-28-4
-
-
Carc. 2
Details
reaction products of diisopropanolamine with formaldehyde (1:4)
432-440-8
220444-73-5
Carc. 2
Details
Reaction product of: acetophenone, formaldehyde, cyclohexylamine, methanol and acetic acid
R633
406-230-1
224635-63-6
Carc. 2
Details
reaction mass of: reaction product of 4,4'-methylenebis[2-(4-hydroxybenzyl)-3,6-dimethylphenol] and 6-diazo-5,6-dihydro-5-oxo-naphthalenesulfonate (1:2); reaction product of 4,4'-methylenebis[2-(4-hydroxybenzyl)-3,6-dimethylphenol] and 6-diazo-5,6-dihydro-5-oxo-naphthalenesulfonate (1:3)
T-271
417-980-4
157321-59-0
Carc. 2
Details
reaction mass of: diester of 4,4'-methylenebis[2-(2-hydroxy-5-methylbenzyl)-3,6-dimethylphenol] and 6-diazo-5,6-dihydro-5-oxonaphthalene-1-sulfonic acid (1:2); triester of 4,4'-methylenebis[2-(2-hydroxy-5-methylbenzyl)-3,6-dimethylphenol] and 6-diazo-5,6-dihydro-5-oxonaphthalene-1-sulfonic acid (1:3)
427-140-9
-
Carc. 2
Details
reaction mass of: 4-(7-hydroxy-2,4,4-trimethyl-2-chromanyl)resorcinol-4-yl-tris(6-diazo-5,6-dihydro-5-oxonaphthalen-1-sulfonate); 4-(7-hydroxy-2,4,4-trimethyl-2-chromanyl)resorcinolbis(6-diazo-5,6-dihydro-5-oxonaphthalen-1-sulfonate) (2:1)
T-69
414-770-4
140698-96-0
Carc. 2
Details
reaction mass of: 2,2'-[(3,3'-dichloro[1,1'-biphenyl]-4,4'-diyl)bis(azo)]bis[N-(2,4-dimethylphenyl)]-3-oxo-butanamide; 2-[[3,3'-dichloro-4'-[[1[[(2,4-dimethylphenyl)amino]carbonyl]-2-oxopropyl]azo][1,1'biphenyl]-4-yl]azo]-N-(2-methylphenyl)-3-oxo-butanamide; 2-[[3,3'-dichloro-4'-[[1[[(2,4-dimethylphenyl)amino]carbonyl]-2-oxopropyl]azo][1,1'-biphenyl]-4-yl]azo]-N-(2-carboxylphenyl)-3-oxo-butanamide
434-330-5
-
Carc. 2
Details
proquinazid (ISO); 6-iodo-2-propoxy-3-propylquinazolin-4(3H)-one
606-168-7
189278-12-4
Carc. 2
Details
propyzamide (ISO); 3,5-dichloro-N-(1,1-dimethylprop-2-ynyl)benzamide
245-951-4
23950-58-5
Carc. 2
Details
propazine (ISO);2-chloro-4,6-bis(isopropylamino)-1,3,5-triazine
205-359-9
139-40-2
Carc. 2
Details
propargite (ISO); 2-(4-tert-butylphenoxy)cyclohexyl prop-2-ynyl sulphite
219-006-1
2312-35-8
Carc. 2
Details
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