pregnant-women-protection

Protection of Pregnant and Breastfeeding Workers Directive, Annex I+II

EU. Chemical Agents: Annexes I & II, Directive 92/85/EEC on Pregnant Workers, 28 November 1992 (updated by table 3 of Annex VI to CLP, 5 October 2018)

This list contains a non-exhaustive inventory of substances to which pregnant workers and workers who have recently given birth or are breastfeeding may not be exposed. Employers are obligated to prevent the exposure of these workers to any agents that may have adverse health effects on either mother or child. The inventory originates from Table 3 of Annex VI to the CLP.

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Last updated 23 April 2024. Database contains 2100 unique substances/entries.
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Substance Name
EC No.
CAS No.
CLP (1272/2008) CMRs
ECCAR Directive 2004/37/EC
 
spirodiclofen (ISO); 3-(2,4-dichlorophenyl)-2-oxo-1-oxaspiro[4.5]dec-3-en-4-yl 2,2-dimethylbutyrate
604-636-5
148477-71-8
Carc. 1B; Repr. 2
yes
 Details
tetrasodium 3,3'-[[1,1'-biphenyl]-4,4'diylbis(azo)]bis[5-amino-4-hydroxynaphthalene-2,7-disulphonate]; C.I. Direct Blue 6
220-012-1
2602-46-2
Carc. 1B; Repr. 2
yes
 Details
α, α, α,4-tetrachlorotoluene; p-chlorobenzotrichloride
226-009-1
5216-25-1
Carc. 1B; Repr. 2
yes
 Details
butanone oxime; ethyl methyl ketoxime; ethyl methyl ketone oxime
202-496-6
96-29-7
Carc. 1B; STOT SE 1
yes
 Details
(3-chloro-2-hydroxypropyl); trimethylammonium chloride ... %
222-048-3
3327-22-8
Carc. 2
Details
(4-phenylbutyl)phosphinic acid
420-450-5
86552-32-1
Carc. 2
Details
(5-chloro-2-methoxy-4-methyl-3-pyridyl) (4,5,6-trimethoxy-o-tolyl)methanone; pyriofenone
692-456-8
688046-61-9
Carc. 2
Details
(Z)-2-methoxymino-2-[2-(tritylamino)thiazol-4-yl]acetic acid
431-520-1
64485-90-1
Carc. 2
Details
1,1,2-trichloroethane
201-166-9
79-00-5
Carc. 2
Details
1,1-dichloroethylene; vinylidene chloride
200-864-0
75-35-4
Carc. 2
Details
1,2,3,4,5,6-hexachlorcyclohexanes with the exception of those specified elsewhere in this Annex
210-168-9
608-73-1
Carc. 2
Details
1,2-epoxybutane
203-438-2
106-88-7
Carc. 2
Details
1,3,5-triazine-2,4,6-triamine; melamine
203-615-4
108-78-1
Carc. 2
Details
1,4-dichlorobenzene; p-dichlorobenzene
203-400-5
106-46-7
Carc. 2
Details
1,5-naphthylenediamine
218-817-8
2243-62-1
Carc. 2
Details
1-bromo-2-methylpropyl propionate
422-900-6
158894-67-8
Carc. 2
Details
1-bromo-3,4,5-trifluorobenzene
1-BROM-3,4,5-TRIFLUORBENZOL; 1-BROMO-3,4,5-TRIFLUOROBENZENE
418-480-9
138526-69-9
Carc. 2
Details
1-vinyl-2-pyrrolidone
201-800-4
88-12-0
Carc. 2
Details
2,2'-((3,3', 5,5'-tetramethyl-(1,1'-biphenyl)-4,4'-diyl)-bis(oxymethylene))-bis-oxirane
EPIKOTE YX4000; EPIKOTE YX4000H; YX-4000
413-900-7
85954-11-6
Carc. 2
Details
2,2'-methylenediphenyl diisocyanate; diphenylmethane-2,2'-diisocyanate
219-799-4
2536-05-2
Carc. 2
Details
2,2-dibromo-2-nitroethanol
PERMACHEM N21
412-380-9
69094-18-4
Carc. 2
Details
2,3,4-trichlorobut-1-ene
219-397-9
2431-50-7
Carc. 2
Details
2,4,6-trichlorophenol
201-795-9
88-06-2
Carc. 2
Details
2,6-xylidine; 2,6-dimethylaniline
201-758-7
87-62-7
Carc. 2
Details
2-ethyl-2-[[(1-oxoallyl)oxy]methyl]-1,3-propanediyl diacrylate; 2,2-bis(acryloyloxymethyl)butyl acrylate; trimethylolpropane triacrylate
239-701-3
15625-89-5
Carc. 2
Details
2-ethylphenylhydrazine hydrochloride
2-EPH
421-460-2
19398-06-2
Carc. 2
Details
2-furaldehyde
202-627-7
98-01-1
Carc. 2
Details
2-methyl-m-phenylene diisocyanate; toluene-2,4-di-isocyanate
202-039-0
91-08-7
Carc. 2
Details
3,3'-dimethylbiphenyl-4,4'-diyl diisocyanate
202-112-7
91-97-4
Carc. 2
Details
3,5,5-trimethylcyclohex-2-enone; isophorone
201-126-0
78-59-1
Carc. 2
Details
3-(4-chlorophenyl)-1,1-dimethyluronium trichloroacetate; monuron-TCA
620-358-7
140-41-0
Carc. 2
Details
4,4'-bis(N-carbamoyl-4-methylbenzenesulfonamide)diphenylmethane
B-TUM
418-770-5
151882-81-4
Carc. 2
Details
4,4'-carbonimidoylbis[N, N-dimethylaniline]
207-762-5
492-80-8
Carc. 2
Details
4,4'-methylenebis(2-ethylaniline); 4,4'-methylenebis(2-ethylbenzeneamine)
243-420-1
19900-65-3
Carc. 2
Details
4,4'-methylenediphenyl diisocyanate; diphenylmethane-4,4'-diisocyanate
202-966-0
101-68-8
Carc. 2
Details
4-[4-(1,3-dihydroxyprop-2-yl)phenylamino]-1,8-dihydroxy-5-nitroanthraquinone
ANTHRACHINON BLAU 27 HD
406-057-1
114565-66-1
Carc. 2
Details
4-methyl-m-phenylene diisocyanate; toluene-2,6-di-isocyanate
209-544-5
584-84-9
Carc. 2
Details
4-methylpentan-2-one; isobutyl methyl ketone
203-550-1
108-10-1
Carc. 2
Details
4-vinylcyclohexene
202-848-9
100-40-3
Carc. 2
Details
5-fluoro-1,3-dimethyl-N-[2-(4-methylpentan-2-yl)phenyl]-1H-pyrazole-4-carboxamide; 2'-[(RS)-1,3-dimethylbutyl]-5-fluoro-1,3-dimethylpyrazole-4-carboxanilide; penflufen
619-823-7
494793-67-8
Carc. 2
Details
5-nitro-o-toluidine
202-765-8
99-55-8
Carc. 2
Details
5-nitro-o-toluidine hydrochloride
256-960-8
51085-52-0
Carc. 2
Details
6,6'-bis(diazo-5,5', 6,6'-tetrahydro-5,5'-dioxo)[methylene-bis(5-(6-diazo-5,6-dihydro-5-oxo-1-naphthylsulphonyloxy)-6-methyl-2-phenylene]di(naphthalene-1-sulfonate)
441-550-5
-
Carc. 2
Details
acetamide
200-473-5
60-35-5
Carc. 2
Details
aclonifen (ISO); 2-chloro-6-nitro-3-phenoxyaniline
277-704-1
74070-46-5
Carc. 2
Details
alachlor (ISO); 2-chloro-2',6'-diethyl-N-(methoxymethyl)acetanilide
240-110-8
15972-60-8
Carc. 2
Details
aldrin (ISO)
206-215-8
309-00-2
Carc. 2
Details
alkanes, C10-13, chloro; chlorinated paraffins, C10-13
287-476-5
85535-84-8
Carc. 2
Details
amisulbrom (ISO); 3-(3-bromo-6-fluoro-2-methylindol-1-ylsulfonyl)-N,N-dimethyl-1H-1,2,4-triazole-1-sulfonamide
672-776-4
348635-87-0
Carc. 2
Details
antimony trioxide
215-175-0
1309-64-4
Carc. 2
Details
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