pregnant-women-protection

Protection of Pregnant and Breastfeeding Workers Directive, Annex I+II

EU. Chemical Agents: Annexes I & II, Directive 92/85/EEC on Pregnant Workers, 28 November 1992 (updated by table 3 of Annex VI to CLP, 5 October 2018)

This list contains a non-exhaustive inventory of substances to which pregnant workers and workers who have recently given birth or are breastfeeding may not be exposed. Employers are obligated to prevent the exposure of these workers to any agents that may have adverse health effects on either mother or child. The inventory originates from Table 3 of Annex VI to the CLP.

Last updated 25 April 2024. Database contains 2100 unique substances/entries.

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Showing 901 - 1,000 of 2,100 results.

Substance Name	EC No.	CAS No.	CLP (1272/2008) CMRs	ECCAR Directive 2004/37/EC
α-chlorotoluene; benzyl chloride	202-853-6	100-44-7	Carc. 1B	yes	Details
(R)-α-phenylethylammonium(-)-(1R, 2S)-(1,2-epoxypropyl)phosphonate monohydrate PHENETHYLAMMONIUM SALT OF FOSFOMYCIN	418-570-8	25383-07-7	Repr. 2		Details
1,2,4-triazole	206-022-9	288-88-0	Repr. 1B	yes	Details
1,3,5-tris(oxiranylmethyl)-1,3,5-triazine-2,4,6(1H,3H,5H)-trione; TGIC	219-514-3	2451-62-9	Muta. 1B	yes	Details
1,4,5,8-tetraaminoanthra; quinone; C.I. Disperse Blue 1	219-603-7	2475-45-8	Carc. 1B	yes	Details
1,5-naphthylenediamine	218-817-8	2243-62-1	Carc. 2		Details
1-(2-amino-5-chlorophenyl)-2,2,2-trifluoro-1,1-ethanediol, hydrochloride [containing ≥ 0,1 % 4-chloroaniline (EC No 203-401-0)]	433-580-2	214353-17-0	Carc. 1B	yes	Details
2,2'-methylenediphenyl diisocyanate; diphenylmethane-2,2'-diisocyanate	219-799-4	2536-05-2	Carc. 2		Details
2,3,4-trichlorobut-1-ene	219-397-9	2431-50-7	Carc. 2		Details
2,3,5,6-tetrafluoro-4-(methoxymethyl)benzyl (1R,3R)-2,2-dimethyl-3-[(1Z)-prop-1-en-1-yl]cyclopropanecarboxylate; epsilon-metofluthrin	-	240494-71-7	STOT SE 1		Details
2,3-epoxypropyl o-tolyl ether	218-645-3	2210-79-9	Muta. 2		Details
2,4,5-trimethylaniline hydrochloride	-	21436-97-5	Carc. 1B	yes	Details
2-chloro-6-fluoro-phenol	433-890-8	2040-90-6	Muta. 1B; Repr. 2	yes	Details
3-chloro-4-(3-fluorobenzyloxy)aniline	445-590-4	202197-26-0	Muta. 2		Details
6-[(C10-C13)-alkyl-(branched, unsaturated)-2,5-dioxopyrrolidin-1-yl]hexanoic acid	701-118-1	2156592-54-8	Repr. 1B	yes	Details
6-glycidyloxynapht-1-yl oxymethyloxirane	429-960-2	27610-48-6	Muta. 2		Details
[(m-tolyloxy)methyl]oxirane	218-575-3	2186-25-6	Muta. 2		Details
[(p-tolyloxy)methyl]oxirane	218-574-8	2186-24-5	Muta. 2		Details
[(tolyloxy)methyl]oxirane; cresyl glycidyl ether	247-711-4	26447-14-3	Muta. 2		Details
ammonium perfluorooctanesulfonate; ammonium heptadecafluorooctanesulfonate	249-415-0	29081-56-9	Carc. 2; Repr. 1B	yes	Details
bentazone (ISO); 3-isopropyl-2,1,3-benzothiadiazine-4-one-2,2-dioxide	246-585-8	25057-89-0	Repr. 2		Details
benz[e]acephenanthrylene	205-911-9	205-99-2	Carc. 1B	yes	Details
benzidine sulphate	244-236-4	21136-70-9	Carc. 1A	yes	Details
benzo[j]fluoranthene	205-910-3	205-82-3	Carc. 1B	yes	Details
benzo[k]fluoranthene	205-916-6	207-08-9	Carc. 1B	yes	Details
benzyl 2,4-dibromobutanoate B2,4DBB	420-710-8	23085-60-1	Repr. 2		Details
bromadiolone (ISO); 3-[3-(4'-bromobiphenyl-4-yl)-3-hydroxy-1-phenylpropyl]-4-hydroxy-2H-chromen-2-one	249-205-9	28772-56-7	Repr. 1B	yes	Details
butyl glycidyl ether; butyl 2,3-epoxypropyl ether	219-376-4	2426-08-6	Carc. 2; Muta. 2		Details
C.I. Disperse Yellow 3; N-[4-[(2-hydroxy-5-methylphenyl)azo]phenyl]acetamide	220-600-8	2832-40-8	Carc. 2		Details
cadmium hydroxide; cadmium dihydroxide	244-168-5	21041-95-2	Carc. 1B; Muta. 1B	yes	Details
captafol (ISO);1,2,3,6-tetrahydro-N-(1,1,2,2- tetrachloroethylthio)phthalimide	219-363-3	2425-06-1	Carc. 1B	yes	Details
chrysene	205-923-4	218-01-9	Carc. 1B; Muta. 2	yes	Details
citric acid, nickel salt	245-119-0	22605-92-1	Carc. 1A; Muta. 2; Repr. 1B	yes	Details
clothianidin (ISO); (E)-1-(2-chloro-1,3-thiazol-5-ylmethyl)-3-methyl-2-nitroguanidine	433-460-1	210880-92-5	Repr. 2; STOT SE 1		Details
di-allate (ISO); S-(2,3-dichloroallyl)-N,N-diisopropylthiocarbamate	218-961-1	2303-16-4	Carc. 2		Details
dibutylbis(pentane-2,4-dionato-O,O')tin	245-152-0	22673-19-4	Repr. 1B	yes	Details
dibutyltin bis (2-ethylhexanoate)	220-481-2	2781-10-4	Muta. 2; Repr. 1B	yes	Details
dichromium tris(chromate); chromium III chromate; chromic chromate	246-356-2	24613-89-6	Carc. 1B	yes	Details
diisooctyl phthalate	248-523-5	27554-26-3	Repr. 1B	yes	Details
dinitrotoluene	246-836-1	25321-14-6	Carc. 1B; Muta. 2; Repr. 2	yes	Details
dodecachloropentacyclo[5.2.1.02,6.03,9.05,8]decane; mirex	219-196-6	2385-85-5	Carc. 2; Repr. 2		Details
etridiazole (ISO); 5-ethoxy-3-trichloromethyl-1,2,4-thiadiazole	219-991-8	2593-15-9	Carc. 2		Details
fluopicolide (ISO); 2,6-dichloro-N-[3-chloro-5-(trifluoromethyl)-2-pyridylmethyl]benzamide	607-285-6	239110-15-7	Repr. 2		Details
hexabromocyclododecane show/hide gamma-hexabromocyclododecane EC / List no: 603-804-5 \| CAS no: 134237-52-8 beta-hexabromocyclododecane EC / List no: 603-802-4 \| CAS no: 134237-51-7 Hexabromocyclododecane EC / List no: 247-148-4 \| CAS no: 25637-99-4 1,2,5,6,9,10-hexabromocyclodecane EC / List no: 221-695-9 \| CAS no: 3194-55-6 alpha-hexabromocyclododecane EC / List no: 603-801-9 \| CAS no: 134237-50-6	247-148-4	25637-99-4	Repr. 2		Details
hydroxylamine phosphate	244-077-0	20845-01-6	Carc. 2		Details
imidazole	206-019-2	288-32-4	Repr. 1B	yes	Details
indium phosphide	244-959-5	22398-80-7	Carc. 1B; Repr. 2	yes	Details
lead hexafluorosilicate	247-278-1	25808-74-6	Repr. 1A	yes	Details
lenacil (ISO); 3-cyclohexyl-6,7- dihydro-1H-cyclopenta[d]pyrimidine-2,4(3H,5H)-dione	218-499-0	2164-08-1	Carc. 2		Details
leptophos (ISO); O-4-bromo-2,5-dichlorophenyl O-methyl phenylphosphorothioate	244-472-8	21609-90-5	STOT SE 1		Details
lithium perfluorooctane sulfonate; lithium heptadecafluorooctanesulfonate	249-644-6	29457-72-5	Carc. 2; Repr. 1B	yes	Details
m-tolylidene diisocyanate; toluene-diisocyanate	247-722-4	26471-62-5	Carc. 2		Details
malachite green oxalate	219-441-7	2437-29-8	Repr. 2		Details
methyl N-(isopropoxycarbonyl)-L-valyl-(3RS)-3-(4-chlorophenyl)-β-alaninate; valifenalate	608-192-3	283159-90-0	Carc. 2		Details
methyl-phenylene diamine	246-910-3	25376-45-8	Carc. 1B; Muta. 2; Repr. 2	yes	Details
methylenediphenyl diisocyanate	247-714-0	26447-40-5	Carc. 2		Details
molinate (ISO);S-ethyl 1-perhydroazepinecarbothioate; S-ethyl perhydroazepine-1-carbothioate	218-661-0	2212-67-1	Carc. 2; Repr. 2		Details
N, N',N''-tris(2-methyl-2,3-epoxypropyl)-perhydro-2,4,6-oxo-1,3,5-triazine	435-010-8	26157-73-3	Muta. 2		Details
N, N-(dimethylamino)thioacetamide hydrochloride	435-470-1	27366-72-9	Repr. 1B	yes	Details
N-ethyl-2-pyrrolidone; 1-ethylpyrrolidin-2-one	220-250-6	2687-91-4	Repr. 1B	yes	Details
nickel arsenide	248-169-1	27016-75-7	Carc. 1A	yes	Details
nickel hexafluorosilicate	247-430-7	26043-11-8	Carc. 1A; Muta. 2; Repr. 1B	yes	Details
nickel isooctanoate	248-585-3	27637-46-3	Carc. 1A; Muta. 2; Repr. 1B	yes	Details
nickel(II) isooctanoate	249-555-2	29317-63-3	Carc. 1A; Muta. 2; Repr. 1B	yes	Details
nickel(II) silicate	244-578-4	21784-78-1	Carc. 1A	yes	Details
nickel(II) stearate; nickel(II) octadecanoate	218-744-1	2223-95-2	Carc. 1A; Muta. 2; Repr. 1B	yes	Details
nonylphenol	246-672-0	25154-52-3	Repr. 2		Details
oxalic acid, nickel salt	243-867-2	20543-06-0	Carc. 1A	yes	Details
perfluorononan-1-oic acid sodium salts	-	21049-39-8	Carc. 2; Repr. 1B	yes	Details
phenol, 4-dodecyl-, branched	640-104-9	210555-94-5	Repr. 1B	yes	Details
phenylhydrazine hydrochloride	248-259-0	27140-08-5	Carc. 1B; Muta. 2	yes	Details
pinoxaden (ISO); 8-(2,6-diethyl-4-methylphenyl)-7-oxo-1,2,4,5-tetrahydro-7H-pyrazolo[1,2-d][1,4,5]oxadiazepin-9-yl 2,2-dimethylpropanoate	635-361-9	243973-20-8	Repr. 2		Details
pirimicarb (ISO); 2-(dimethylamino)-5,6-dimethylpyrimidin-4-yl dimethylcarbamate	245-430-1	23103-98-2	Carc. 2		Details
polyhexamethylene biguanide hydrochloride; PHMB	608-042-7	27083-27-8	Carc. 2		Details
potassium perfluorooctanesulfonate; potassium heptadecafluorooctane-1-sulfonate	220-527-1	2795-39-3	Carc. 2; Repr. 1B	yes	Details
propargite (ISO); 2-(4-tert-butylphenoxy)cyclohexyl prop-2-ynyl sulphite	219-006-1	2312-35-8	Carc. 2		Details
propylenethiourea	620-432-9	2122-19-2	Repr. 2		Details
propyzamide (ISO); 3,5-dichloro-N-(1,1-dimethylprop-2-ynyl)benzamide	245-951-4	23950-58-5	Carc. 2		Details
quinoclamine (ISO); 2-amino-3-chloro-1,4-naphthoquinonequinoclamine (ISO); 2-amino-3-chloro-1,4-naphthoquinone	220-529-2	2797-51-5	Carc. 2; Repr. 2		Details
quinomethionate; chinomethionat (ISO); 6-methyl-1,3-dithiolo(4,5-b)quinoxalin-2-one	219-455-3	2439-01-2	Repr. 2		Details
Reaction product of: acetophenone, formaldehyde, cyclohexylamine, methanol and acetic acid R633	406-230-1	224635-63-6	Carc. 2		Details
reaction products of diisopropanolamine with formaldehyde (1:4)	432-440-8	220444-73-5	Carc. 2		Details
spirotetramat (ISO); (5s,8s)-3- (2,5-dimethylphenyl)-8-methoxy-2-oxo-1-azaspiro[4,5]dec- 3-en-4-yl ethyl carbonate	606-523-6	203313-25-1	Repr. 2		Details
tetrasodium 3,3'-[[1,1'-biphenyl]-4,4'diylbis(azo)]bis[5-amino-4-hydroxynaphthalene-2,7-disulphonate]; C.I. Direct Blue 6	220-012-1	2602-46-2	Carc. 1B; Repr. 2	yes	Details
thiophanate-methyl (ISO); dimethyl (1,2-phenylenedicarbamothioyl)biscarbamate; dimethyl 4,4'-(o-phenylene) bis(3-thioallophanate)	245-740-7	23564-05-8	Carc. 2; Muta. 2		Details
triammonium 4-[4-[7-(4-carboxylatoanilino)-1-hydroxy3-sulfonato-2-naphthylazo]-2,5-dimethoxyphenylazo]benzoate	432-270-4	221354-37-6	Repr. 2		Details
tridemorph (ISO); 2,6-dimethyl-4-tridecylmorpholine	246-347-3	24602-86-6	Repr. 1B	yes	Details
trifluoroiodomethane; trifluoromethyl iodide	219-014-5	2314-97-8	Muta. 2		Details
trixylyl phosphate	246-677-8	25155-23-1	Repr. 1B	yes	Details
valinamide D,L-VALINEAMIDE	402-840-7	20108-78-5	Repr. 2		Details
(3-chloro-2-hydroxypropyl); trimethylammonium chloride ... %	222-048-3	3327-22-8	Carc. 2		Details
1,2,5,6,9,10-hexabromocyclododecane	221-695-9	3194-55-6	Repr. 2		Details
2,2-bis(bromomethyl)propane-1,3-diol	221-967-7	3296-90-0	Carc. 1B; Muta. 1B	yes	Details
2,2-dimethylpropan-1-ol, tribromo derivative	253-057-0	36483-57-5	Carc. 1B; Muta. 2	yes	Details
2,3-epoxypropyltrimethylammonium chloride ... %; glycidyl trimethylammonium chloride ... %	221-221-0	3033-77-0	Carc. 1B; Muta. 2; Repr. 2	yes	Details
2,4-diaminoanisole sulphate	254-323-9	39156-41-7	Carc. 1B; Muta. 2	yes	Details
2-methoxyethyl acrylate	221-499-3	3121-61-7	Muta. 2; Repr. 1B	yes	Details
3-oxoandrost-4-ene-17-β-carboxylic acid CC14837; SKF 106224	414-990-0	302-97-6	Repr. 2		Details
4-amino-3-fluorophenol FAP	402-230-0	399-95-1	Carc. 1B	yes	Details
4-chloro-o-toluidine hydrochloride	221-627-8	3165-93-3	Carc. 1B; Muta. 2	yes	Details

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pregnant-women-protection

pregnant-women-protection

Protection of Pregnant and Breastfeeding Workers Directive, Annex I+II

EU. Chemical Agents: Annexes I & II, Directive 92/85/EEC on Pregnant Workers, 28 November 1992 (updated by table 3 of Annex VI to CLP, 5 October 2018)

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Last updated 25 April 2024. Database contains 2100 unique substances/entries.

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