pregnant-women-protection

Protection of Pregnant and Breastfeeding Workers Directive, Annex I+II

EU. Chemical Agents: Annexes I & II, Directive 92/85/EEC on Pregnant Workers, 28 November 1992 (updated by table 3 of Annex VI to CLP, 5 October 2018)

This list contains a non-exhaustive inventory of substances to which pregnant workers and workers who have recently given birth or are breastfeeding may not be exposed. Employers are obligated to prevent the exposure of these workers to any agents that may have adverse health effects on either mother or child. The inventory originates from Table 3 of Annex VI to the CLP.

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Last updated 16 April 2024. Database contains 2100 unique substances/entries.
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Substance Name
EC No.
CAS No.
CLP (1272/2008) CMRs
ECCAR Directive 2004/37/EC
 
coumatetralyl; 4-hydroxy-3-(1,2,3,4-tetrahydro-1-naphthyl)coumarin
227-424-0
5836-29-3
Repr. 1B
yes
 Details
cyclic 3-(1,2-ethanediylacetale)-estra-5(10),9(11)-diene-3,17-dione
427-230-8
5571-36-8
Repr. 1B
yes
 Details
cymoxanil (ISO); 2-cyano-N-[(ethylamino)carbonyl]-2-(methoxyimino)acetamide
261-043-0
57966-95-7
Repr. 2
Details
DDT (ISO); clofenotane (INN); dicophane;1,1,1-trichloro-2,2-bis(4-chlorophenyl)ethane; dichlorodiphenyltrichloroethane
200-024-3
50-29-3
Carc. 2
Details
dibenz[a,h]anthracene
200-181-8
53-70-3
Carc. 1B
yes
 Details
disodium 3,3'-[[1,1'-biphenyl]-4,4'-diylbis(azo)]bis(4-aminonaphthalene-1-sulphonate); C.I. Direct Red 28
209-358-4
573-58-0
Carc. 1B; Repr. 2
yes
 Details
DNOC (ISO); 4,6-dinitro-o-cresol
208-601-1
534-52-1
Muta. 2
Details
fenthion (ISO); O, O-dimethyl-O-(4-methylthion-m-tolyl) phosphorothioate
200-231-9
55-38-9
Muta. 2
Details
formaldehyde ... %
200-001-8
50-00-0
Carc. 1B; Muta. 2
yes
 Details
hexan-2-one; methyl butyl ketone; butyl methyl ketone; methyl-n-butyl ketone
209-731-1
591-78-6
Repr. 2
Details
hydroxylamine 4-methylbenzenesulfonate
258-872-5
53933-48-5
Carc. 2
Details
hydroxylammonium chloride; hydroxylamine hydrochloride
226-798-2
5470-11-1
Carc. 2
Details
isobutyl nitrite
208-819-7
542-56-3
Carc. 1B; Muta. 2
yes
 Details
lindane (ISO); γ-HCH or γ-BHC; γ-1,2,3,4,5,6-hexachlorocyclohexane
200-401-2
58-89-9
Details
m-phenylenediamine dihydrochloride
208-790-0
541-69-5
Muta. 2
Details
malachite green hydrochloride
209-322-8
569-64-2
Repr. 2
Details
methyl-ONN-azoxymethyl acetate; methyl azoxy methyl acetate
209-765-7
592-62-1
Carc. 1B; Repr. 1B
yes
 Details
N,N'-methylenedimorpholine; N,N'-methylenebismorpholine [formaldehyde released from N,N'-methylenebismorpholine]; [MBM]
227-062-3
5625-90-1
Carc. 1B; Muta. 2
yes
 Details
N,N-dimethylhydrazine
200-316-0
57-14-7
Carc. 1B
yes
 Details
neodecanoic acid, nickel salt
257-447-1
51818-56-5
Carc. 1A; Muta. 2; Repr. 1B
yes
 Details
nickel 3,5-bis(tert-butyl)-4-hydroxybenzoate (1:2)
258-051-1
52625-25-9
Carc. 1A; Muta. 2; Repr. 1B
yes
 Details
nickel dibenzoate
209-046-8
553-71-9
Carc. 1A; Muta. 2; Repr. 1B
yes
 Details
nickel dicyanide
209-160-8
557-19-7
Carc. 1A
yes
 Details
nickel divanadium hexaoxide
257-970-5
52502-12-2
Carc. 1A
yes
 Details
nickel oxalate
208-933-7
547-67-1
Carc. 1A
yes
 Details
Noise
209-217-7
561-27-3
Details
o-(p-isocyanatobenzyl)phenyl isocyanate; diphenylmethane-2,4'-diisocyanate
227-534-9
5873-54-1
Carc. 2
Details
octamethylcyclotetrasiloxane; [D4]
209-136-7
556-67-2
Repr. 2
Details
phenylhydrazinium chloride
200-444-7
59-88-1
Carc. 1B; Muta. 2
yes
 Details
phenylhydrazinium sulphate; (2:1)
257-622-2
52033-74-6
Carc. 1B; Muta. 2
yes
 Details
R-1-chloro-2,3-epoxypropane
(R)-EPICHLOROHYDRIN
424-280-2
51594-55-9
Carc. 1B
yes
 Details
R—2,3-epoxy-1-propanol
R-GLYCIDOL
404-660-4
57044-25-4
Carc. 1B; Muta. 2; Repr. 1B
yes
 Details
theophylline; 1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione
200-385-7
58-55-9
Repr. 1B
yes
 Details
toluidine sulphate (1:1)
208-741-3
540-25-0
Carc. 2
Details
toluidinium chloride
208-740-8
540-23-8
Carc. 2
Details
triadimenol (ISO); (1RS,2RS;1RS,2SR)-1-(4-chlorophenoxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol; α-tert-butyl-β-(4-chlorophenoxy)-1H-1,2,4-triazole-1-ethanol
259-537-6
55219-65-3
Repr. 1B
yes
 Details
trimethylopropane tri(3-aziridinylpropanoate); (TAZ)
257-765-0
52234-82-9
Muta. 2
Details
trisodium nitrilotriacetate
225-768-6
5064-31-3
Carc. 2
Details
urethane (INN); ethyl carbamate
200-123-1
51-79-6
Carc. 1B
yes
 Details
vinclozolin (ISO); N-3,5-dichlorophenyl-5-methyl-5-vinyl-1,3-oxazolidine-2,4-dione
256-599-6
50471-44-8
Carc. 2; Repr. 1B
yes
 Details
α, α, α,4-tetrachlorotoluene; p-chlorobenzotrichloride
226-009-1
5216-25-1
Carc. 1B; Repr. 2
yes
 Details
(3,3'-Dimethyl(1,1'-biphenyl)-4,4'-diyl)diammonium bis(hydrogen sulphate)
265-294-7
64969-36-4
Carc. 1B
yes
 Details
(3-chlorophenyl)-(4-methoxy-3-nitrophenyl)methanone
T 1569; T001569
423-290-4
66938-41-8
Muta. 2
Details
(5-chloro-2-methoxy-4-methyl-3-pyridyl) (4,5,6-trimethoxy-o-tolyl)methanone; pyriofenone
692-456-8
688046-61-9
Carc. 2
Details
(Z)-2-methoxymino-2-[2-(tritylamino)thiazol-4-yl]acetic acid
431-520-1
64485-90-1
Carc. 2
Details
1,2,3,4,5,6-hexachlorcyclohexanes with the exception of those specified elsewhere in this Annex
210-168-9
608-73-1
Carc. 2
Details
1,2-benzenedicarboxylic acid, dihexyl ester, branched and linear
271-093-5
68515-50-4
Repr. 1B
yes
 Details
1,2-benzenedicarboxylic acid; di-C7-11-branched and linear alkylesters
271-084-6
68515-42-4
Repr. 1B
yes
 Details
1,2-diethoxyethane
211-076-1
629-14-1
Repr. 1A
yes
 Details
1,4-Benzenediamine, N,N'-mixed Ph and tolyl derivs.
273-227-8
68953-84-4
Repr. 1B
yes
 Details
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