pregnant-women-protection

Protection of Pregnant and Breastfeeding Workers Directive, Annex I+II

EU. Chemical Agents: Annexes I & II, Directive 92/85/EEC on Pregnant Workers, 28 November 1992 (updated by table 3 of Annex VI to CLP, 5 October 2018)

This list contains a non-exhaustive inventory of substances to which pregnant workers and workers who have recently given birth or are breastfeeding may not be exposed. Employers are obligated to prevent the exposure of these workers to any agents that may have adverse health effects on either mother or child. The inventory originates from Table 3 of Annex VI to the CLP.

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Last updated 24 April 2024. Database contains 2100 unique substances/entries.
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Substance Name
EC No.
CAS No.
CLP (1272/2008) CMRs
ECCAR Directive 2004/37/EC
 
lead chromate molybdate sulfate red; C.I. Pigment Red 104 [This substance is identified in the Colour Index by Colour Index Constitution Number, C.I. 77605.]
This substance is identified in the Colour Index by Colour Index Constitution Number, C.I. 77605.
235-759-9
12656-85-8
Carc. 1B; Repr. 1A
yes
 Details
lead di(acetate)
206-104-4
301-04-2
Repr. 1A
yes
 Details
lead diazide; lead azide;lead diazide; lead azide [≥ 20 % phlegmatiser]
236-542-1
13424-46-9
Repr. 1A
yes
 Details
lead diazide; lead azide;lead diazide; lead azide [≥ 20 % phlegmatiser]
236-542-1
13424-46-9
Repr. 1A
yes
 Details
lead hexafluorosilicate
247-278-1
25808-74-6
Repr. 1A
yes
 Details
lead hydrogen arsenate
232-064-2
7784-40-9
Carc. 1A; Repr. 1A
yes
 Details
Lead in so far as these agents are capable of being absorbed by the human organism;lead massive: [particle diameter ≥ 1 mm];lead powder [particle diameter < 1 mm]
231-100-4
7439-92-1
Repr. 1A
yes
 Details
Lead in so far as these agents are capable of being absorbed by the human organism;lead massive: [particle diameter ≥ 1 mm];lead powder [particle diameter < 1 mm]
231-100-4
7439-92-1
Details
Lead in so far as these agents are capable of being absorbed by the human organism;lead massive: [particle diameter ≥ 1 mm];lead powder [particle diameter < 1 mm]
231-100-4
7439-92-1
Repr. 1A
yes
 Details
lead sulfochromate yellow; C.I. Pigment Yellow 34 [This substance is identified in the Colour Index by Colour Index Constitution Number, C.I. 77603.]
This substance is identified in the Colour Index by Colour Index Constitution Number, C.I. 77603.
215-693-7
1344-37-2
Carc. 1B; Repr. 1A
yes
 Details
lenacil (ISO); 3-cyclohexyl-6,7- dihydro-1H-cyclopenta[d]pyrimidine-2,4(3H,5H)-dione
218-499-0
2164-08-1
Carc. 2
Details
leptophos (ISO); O-4-bromo-2,5-dichlorophenyl O-methyl phenylphosphorothioate
244-472-8
21609-90-5
STOT SE 1
Details
leucomalachite green; N, N,N',N'-tetramethyl-4,4'-benzylidenedianiline
204-961-9
129-73-7
Carc. 2; Muta. 2
Details
Light oil (coal), coke-oven; Crude benzole [The volatile organic liquid extracted from the gas evolved in the high temperature (greater than 700 °C (1 292 °F)) destructive distillation of coal. Composed primarily of benzene, toluene, and xylenes. May contain other minor hydrocarbon constituents.]
The volatile organic liquid extracted from the gas evolved in the high temperature (greater than 700°C (1292°F)) destructive distillation of coal. Composed primarily of benzene, toluene, and xylenes. May contain other minor hydrocarbon constituents.
266-012-5
65996-78-3
Carc. 1B; Muta. 1B
yes
 Details
Light oil (coal), semi-coking process; Fresh oil [The volatile organic liquid condensed from the gasevolved in the low-temperature (less than 700 °C (1 292 °F)) destructive distillation of coal. Composed primarily of C6-10 hydrocarbons.]
The volatile organic liquid condensed from the gas evolved in the low-temperature (less than 700°C (1292°F)) destructive distillation of coal. Composed primarily of C6-10 hydrocarbons.
292-635-7
90641-11-5
Carc. 1B; Muta. 1B
yes
 Details
Ligroine; Low boiling point naphtha [A complex combination of hydrocarbons obtained by the fractional distillation of petroleum. This fraction boils in a range of approximately 20 °C to 135 °C (58°F to 275°F).]
A complex combination of hydrocarbons obtained by the fractional distillation of petroleum. This fraction boils in a range of approximately 20°C to 135°C (58°F to 275°F).
232-453-7
8032-32-4
Carc. 1B; Muta. 1B
yes
 Details
lindane (ISO); γ-HCH or γ-BHC; γ-1,2,3,4,5,6-hexachlorocyclohexane
200-401-2
58-89-9
Details
linuron (ISO); 3-(3,4-dichlorophenyl)-1-methoxy-1-methylurea
206-356-5
330-55-2
Repr. 1B; Carc. 2
yes
 Details
lithium perfluorooctane sulfonate; lithium heptadecafluorooctanesulfonate
249-644-6
29457-72-5
Carc. 2; Repr. 1B
yes
 Details
Lubricating greases; Grease [A complex combination of hydrocarbons having carbon numbers predominantly in the range of C12 through C50. May contain organic salts of alkali metals, alkaline earth metals, and/or aluminium compounds.]
A complex combination of hydrocarbons having carbon numbers predominantly in the range of C12 through C50. May contain organic salts of alkali metals, alkaline earth metals, and/or aluminium compounds.
278-011-7
74869-21-9
Carc. 1B
yes
 Details
Lubricating oils (petroleum), base oils, paraffinic; Baseoil — unspecified [A complex combination of hydrocarbons obtained by refining of crude oil. It consists predominantly of aromatics, naphthenics and paraffinics and produces a finished oil with a viscosity of 120 SUS at 100 °F (23cSt at 40 °C).]
A complex combination of hydrocarbons obtained by refining of crude oil. It consists predominantly of aromatics, naphthenics and paraffinics and produces a finished oil with a viscosity of 120 SUS at 100°F (23cSt at 40°C).
297-474-6
93572-43-1
Carc. 1B
yes
 Details
Lubricating oils (petroleum), C15-30, hydrotreated neutral oil-based; Baseoil — unspecified [A complex combination of hydrocarbons obtained by treating light vacuum gas oil and heavy vacuum gas oil with hydrogen in the presence of a catalyst in a two stage process with dewaxing being carried out between the two stages. It consists predominantly of hydrocarbons having carbon numbers predominantly in the range of C15 through C30 and produces a finished oil having a viscosity of approximately 15cSt at 40 °C. It contains a relatively large proportion of saturated hydrocabons.]
A complex combination of hydrocarbons obtained by treating light vacuum gas oil and heavy vacuum gas oil with hydrogen in the presence of a catalyst in a two stage process with dewaxing being carried out between the two stages. It consists predominantly of hydrocarbons having carbon numbers predominantly in the range of C15 through C30 and produces a finished oil having a viscosity of approximately 15cSt at 40°C. It contains a relatively large proportion of saturated hydrocarbons.
276-737-9
72623-86-0
Carc. 1B
yes
 Details
Lubricating oils (petroleum), C17-35, solvent-extd., dewaxed, hydrotreated; Baseoil — unspecified
295-423-2
92045-42-6
Carc. 1B
yes
 Details
Lubricating oils (petroleum), C20-50, hydrotreated neutral oil-based, high-viscosity; Baseoil — unspecified [A complex combination of hydrocarbons obtained by treating light vacuum gas oil, heavy vacuum gas oil, and; solvent deasphalted residual oil with hydrogen in the presence of a catalyst in a two stage process with dewaxing being carried out between the two stages. It consists predominantly of hydrocarbons having carbon numbers predominantly in the range of C20 through C50 and produces a finished oil having a viscosity of approximately 112cSt at 40 °C. It contains a relatively large proportion of saturated hydrocarbons.]
A complex combination of hydrocarbons obtained by treating light vacuum gas oil, heavy vacuum gas oil, and solvent deasphalted residual oil with hydrogen in the presence of a catalyst in a two stage process with dewaxing being carried out between the two stages. It consists predominantly of hydrocarbons having carbon numbers predominantly in the range of C20 through C50 and produces a finished oil having a viscosity of approximately 112cSt at 40°C. It contains a relatively large proportion of saturated hydrocarbons.
276-736-3
72623-85-9
Carc. 1B
yes
 Details
Lubricating oils (petroleum), C20-50, hydrotreated neutral oil-based; Baseoil — unspecified [A complex combination of hydrocarbons obtained by treating light vacuum gas oil, heavy vacuum gas oil and solvent deasphalted residual oil with hydrogen in the presence of a catalyst in a two stage process with dewaxing being carried out between the two stages. It consists predominantly of hydrocarbons having carbon numbers predominantly in the range of C20 through C50 and produces a finished oil with a viscosity of approximately 32cSt at 40 °C. It contains a relatively large proportion of saturated hydrocarbons.]
A complex combination of hydrocarbons obtained by treating light vacuum gas oil, heavy vacuum gas oil and solvent deasphalted residual oil with hydrogen in the presence of a catalyst in a two stage process with dewaxing being carried out between the two stages. It consists predominantly of hydrocarbons having carbon numbers predominantly in the range of C20 through C50 and produces a finished oil with a viscosity of approximately 32cSt at 40°C. It contains a relatively large proportion of saturated hydrocarbons.
276-738-4
72623-87-1
Carc. 1B
yes
 Details
Lubricating oils (petroleum), hydrocracked nonarom. solvent-deparaffined; Baseoil — unspecified
295-424-8
92045-43-7
Carc. 1B
yes
 Details
Lubricating oils; Baseoil — unspecified [A complex combination of hydrocarbons obtained from solvent extraction and dewaxing processes. It consists predominantly of saturated hydrocarbons having carbon numbers in the range C15 through C50.]
A complex combination of hydrocarbons obtained from solvent extraction and dewaxing processes. It consists predominantly of saturated hydrocarbons having carbon numbers in the range C15 through C50.
278-012-2
74869-22-0
Carc. 1B
yes
 Details
m-bis(2,3-epoxypropoxy)benzene; resorcinol diglycidyl ether
202-987-5
101-90-6
Carc. 1B; Muta. 2
yes
 Details
m-phenylenediamine
203-584-7
108-45-2
Muta. 2
Details
m-phenylenediamine dihydrochloride
208-790-0
541-69-5
Muta. 2
Details
m-tolylidene diisocyanate; toluene-diisocyanate
247-722-4
26471-62-5
Carc. 2
Details
malachite green hydrochloride
209-322-8
569-64-2
Repr. 2
Details
malachite green oxalate
219-441-7
2437-29-8
Repr. 2
Details
maneb (ISO); manganese ethylenebis(dithiocarbamate) (polymeric)
235-654-8
12427-38-2
Repr. 2
Details
Margosa, ext. [from the kernels of Azadirachta indica extracted with water and further processed with organic solvents]
Extractives and their physically modified derivatives such as tinctures, concretes, absolutes, essential oils, oleoresins, terpenes, terpene-free fractions, distillates, residues, etc., obtained from Azadirachta indica, Meliaceae.
283-644-7
84696-25-3
Repr. 2
Details
Mercury
231-106-7
7439-97-6
Repr. 1B
yes
 Details
mercury dichloride; mercuric chloride
231-299-8
7487-94-7
Muta. 2; Repr. 2
Details
metazachlor (ISO); 2-chloro-N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)-acetamide
266-583-0
67129-08-2
Carc. 2
Details
methanol
200-659-6
67-56-1
STOT SE 1
Details
methoxyacetic acid
210-894-6
625-45-6
Repr. 1B
yes
 Details
methyl iodide; iodomethane
200-819-5
74-88-4
Carc. 2
Details
methyl isocyanate
210-866-3
624-83-9
Repr. 2
Details
methyl salicylate
204-317-7
119-36-8
Repr. 2
Details
methyl-ONN-azoxymethyl acetate; methyl azoxy methyl acetate
209-765-7
592-62-1
Carc. 1B; Repr. 1B
yes
 Details
methyl-phenylene diamine
246-910-3
25376-45-8
Carc. 1B; Muta. 2; Repr. 2
yes
 Details
methylenediphenyl diisocyanate
247-714-0
26447-40-5
Carc. 2
Details
methylhydrazine
200-471-4
60-34-4
Carc. 1B
yes
 Details
methylmercuric chloride
204-064-2
115-09-3
Carc. 2; Repr. 1A
yes
 Details
mipafox (ISO); N,N'-di-isopropylphosphorodiamidic fluoride
206-742-3
371-86-8
STOT SE 1
Details
molinate (ISO);S-ethyl 1-perhydroazepinecarbothioate; S-ethyl perhydroazepine-1-carbothioate
218-661-0
2212-67-1
Carc. 2; Repr. 2
Details
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