Registration Dossier

Diss Factsheets

Physical & Chemical properties

Water solubility

Currently viewing:

Administrative data

Link to relevant study record(s)

Description of key information

The water solubility of p-toluenesulfonyl isocyanate could not be determined experimentally due to its instability in contact with water. Instead, for risk assessment purposes the value for its metabolite p-toluenesulfonamide is used: 3.1 g/L 20ºC.

Key value for chemical safety assessment

Water solubility:
3.1 g/L
at the temperature of:
20 °C

Additional information

Due to its instability in contact with water, the water solubility of p-toluenesulfonyl isocyanate cannot be determined experimentally.

As a value for water solubility is required for risk assessment, the water solubility of the metabolite p-toluenesulfonamide (PTSA, CAS 70-55-3) will be used instead. The water solubility for PTSA, obtained in a non-GLP test according to OECD guideline 105 using the flask method, is 3.1 g/L at 20ºC.