Registration Dossier
Registration Dossier
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The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
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EC number: 223-453-8 | CAS number: 3900-45-6
Acute Toxicity: dermal
Administrative data
- Endpoint:
- acute toxicity: dermal
- Type of information:
- migrated information: read-across based on grouping of substances (category approach)
- Adequacy of study:
- supporting study
- Reliability:
- 4 (not assignable)
Data source
Referenceopen allclose all
- Reference Type:
- publication
- Title:
- Monographs on fragrance raw materials: Benzophenone
- Author:
- Opdyke DLJ
- Year:
- 1 979
- Bibliographic source:
- FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. Volume(issue)/page/year: 11,873,1979
- Reference Type:
- other: Authoritative data base
- Title:
- GCID :38768
- Year:
- 2 011
- Bibliographic source:
- ACToR (Aggregated Computational Toxicology Resource);Food and Cosmetics Toxicology. Vol. 11, Pg. 873, 1973
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other:
- Principles of method if other than guideline:
- Data is from publication
- GLP compliance:
- not specified
- Test type:
- other: no data
- Limit test:
- yes
Test material
- Reference substance name:
- Benzophenone
- EC Number:
- 204-337-6
- EC Name:
- Benzophenone
- Cas Number:
- 119-61-9
- IUPAC Name:
- benzophenone
Constituent 1
Test animals
- Species:
- rabbit
- Strain:
- not specified
- Sex:
- not specified
Administration / exposure
- Type of coverage:
- not specified
- Control animals:
- not specified
Results and discussion
Effect levels
- Sex:
- not specified
- Dose descriptor:
- LD50
- Effect level:
- 3 535 mg/kg bw
- Based on:
- test mat.
Applicant's summary and conclusion
- Interpretation of results:
- not classified
- Remarks:
- Migrated information Criteria used for interpretation of results: EU
- Conclusions:
- Acute dermal toxicity (LD50) value of benzophenone to rabbit on the basis of mortality was obtained at dose concentration 3535 mg/kg bw .This value indicate that benzophenone is non toxic to rabbit by dermal route.
- Executive summary:
Acute dermal toxicity (LD50) value of benzophenone to rabbit on the basis of mortality was obtained at dose concentration 3535 mg/kg bw .This value indicate that benzophenone is non toxic to rabbit by dermal route.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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