Registration Dossier

Administrative data

Endpoint:
acute toxicity: other routes
Type of information:
other: handbook data
Adequacy of study:
supporting study
Study period:
Not stated
Reliability:
3 (not reliable)
Rationale for reliability incl. deficiencies:
other: Peer reviewed handbook citing physical data as found in the literature

Data source

Reference
Reference Type:
review article or handbook
Title:
Patty's Industrial, Hygiene and Toxicology, Thired Revised Edition, Vol 2a, Toxicology
Author:
Clayto G & Clayton F (eds)
Bibliographic source:
pg. 1910

Materials and methods

Principles of method if other than guideline:
Information is presented in a handbook therefore no details are given of methodology or the guidelines followed.
GLP compliance:
not specified

Test material

Reference
Name:
Unnamed
Type:
Constituent

Test animals

Species:
mouse
Strain:
not specified
Sex:
not specified

Administration / exposure

Route of administration:
intravenous
Vehicle:
not specified
Doses:
No avaliable data

Results and discussion

Effect levels
Sex:
not specified
Dose descriptor:
LC50
Effect level:
110 mg/kg bw
Based on:
not specified
Remarks on result:
other: No reliability limits are given

Applicant's summary and conclusion

Conclusions:
The LD50 of the test material was reported to be 110 mg/kg via intraperitoneal administration.

Executive summary:

Information on toxicological properties presented in published handbook. The LD50 of pentafluoride was determined by intraperitoneal administration. The LD50 was determined to be 110 mg/kg. As the data is taken from an handbook, no information is given on methodology or guidelines followed during testing.