Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
acute toxicity: other routes
Type of information:
other: handbook data
Adequacy of study:
supporting study
Study period:
Not stated
Reliability:
3 (not reliable)
Rationale for reliability incl. deficiencies:
other: Peer reviewed handbook citing physical data as found in the literature

Data source

Reference
Reference Type:
review article or handbook
Title:
Patty's Industrial, Hygiene and Toxicology, Thired Revised Edition, Vol 2a, Toxicology
Author:
Clayto G & Clayton F (eds)
Bibliographic source:
pg. 1910

Materials and methods

Principles of method if other than guideline:
Information is presented in a handbook therefore no details are given of methodology or the guidelines followed.
GLP compliance:
not specified

Test material

Constituent 1
Reference substance name:
pentafluoride
IUPAC Name:
pentafluoride

Test animals

Species:
mouse
Strain:
not specified
Sex:
not specified

Administration / exposure

Route of administration:
intravenous
Vehicle:
not specified
Doses:
No avaliable data

Results and discussion

Effect levels
Sex:
not specified
Dose descriptor:
LC50
Effect level:
110 mg/kg bw
Based on:
not specified
Remarks on result:
other: No reliability limits are given

Applicant's summary and conclusion

Conclusions:
The LD50 of the test material was reported to be 110 mg/kg via intraperitoneal administration.

Executive summary:

Information on toxicological properties presented in published handbook. The LD50 of pentafluoride was determined by intraperitoneal administration. The LD50 was determined to be 110 mg/kg. As the data is taken from an handbook, no information is given on methodology or guidelines followed during testing.