Registration Dossier
Registration Dossier
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EC number: 203-910-8 | CAS number: 111-81-9
Endpoint summary
Administrative data
Description of key information
Key value for chemical safety assessment
Skin sensitisation
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not sensitising)
- Additional information:
According to the maximization method of Magnusson and Kligman, no cutaneous reactions attributable to the sensitization potential of the test substance METHYL UNDECYLENATE were observed in guinea-pigs. Five females of the treated group were found dead on day 2, following intradermal injections. Hypoactivity and piloerection were noted between day 5 and day 21 in another animal. These mortalities and clinical signs were attributed to the test substance. No clinical signs and no deaths were noted in the remaining animals. The body weight gain of the remaining animals was normal when compared to that of the control animals.
Migrated from Short description of key information:
A GLP guideline study (OECD 406) was performed in guinea pigs (CIT 1997).
Respiratory sensitisation
Endpoint conclusion
- Additional information:
- Migrated from Short description of key information:
To perform a study on respiratory sensitisation was not required yet for this substance.
Justification for classification or non-classification
According to EU regulation (EC) No. 1272/2008 (CLP) and to EU 67/548/ECC classification system, methyl undec-10 -enoate is not classified.
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