Registration Dossier
Registration Dossier
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EC number: 240-241-0 | CAS number: 16088-62-3
Skin sensitisation
Administrative data
- Endpoint:
- skin sensitisation
- Type of information:
- migrated information: read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- supporting study
- Study period:
- 2002
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: Cited experiments were summarized in the European Chemicals Bureau Methyloxirane (Propylene Oxide) Risk Assessment Report. The original studies were not reviewed.
Cross-reference
- Reason / purpose for cross-reference:
- reference to same study
Data source
Reference
- Reference Type:
- review article or handbook
- Title:
- Unnamed
- Year:
- 2 002
Materials and methods
- GLP compliance:
- not specified
Test material
- Reference substance name:
- propylene oxide
- IUPAC Name:
- propylene oxide
- Reference substance name:
- Methyloxirane
- EC Number:
- 200-879-2
- EC Name:
- Methyloxirane
- Cas Number:
- 75-56-9
- IUPAC Name:
- 2-methyloxirane
Constituent 1
Constituent 2
Results and discussion
Applicant's summary and conclusion
- Interpretation of results:
- not sensitising
- Remarks:
- Migrated information
- Conclusions:
- In this unconventional study, propylene oxide was non-sensitising in the guinea pig.
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