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Ecotoxicological information

Short-term toxicity to aquatic invertebrates

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Description of key information

Key Value has been selected from Seeland publication representing a clearly more sensitive species of daphnids (non-standard test organism) in freshwater. Key value for marine invertebrates has been derived from guideline study with Acartia Tonsa representing marine invertebrates and is the most sensitive value available.

Key value for chemical safety assessment

Fresh water invertebrates

Fresh water invertebrates
Effect concentration:
15.8 mg/L

Marine water invertebrates

Marine water invertebrates
Effect concentration:
44.9 mg/L

Additional information

Five freshwater studies with invertebrates (4 studies with D. magna, 1 study with D. galeata) are available. While the four studies with D. magna show an EC50 (48h) of at least 100 mg/L, an EC50 (48h) of 15.8 mg/L with D. galeata has been observed. The difference in the sensitivity of the species is mostly likely due to the smaller size of D. galeata.

Although the publication has shown some deficiencies in reporting the publication has been selected for the chemical safety assessment as it also has been performed according to the OECD 202 test guideline and the parallel test with D. magna has shown an analogue effect value like the studies from the GLP laboratories indicating a comparable quality standard of the laboratories.

Effects in marine invertebrates has been examined in a study according to ISO/CD 14669 with Tolyltriazole using Acartia Tonsa showing an effect concentration EC50 (48h) = 55 mg/L. Available data on Sodium Benzotriazole with Mysidpsis bahia derived an 96 hour LC50 of 113.57 mg/L (expressed as active ingredient). A study conducted on Sodium Tolytriazole according to

USEPA "Methods for Measuring the Acute Toxicity of Effluents and Receiving Waters to Freshwater and Marine Organisms,”

Fourth Edition,EPA/600/4 -90/027 derived a 96 hour LC50 of 44.9 mg/L.