Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Endpoint summary

Administrative data

Description of key information

Soil macroorganisms

Eisenia andrei reproduction EC10: 22.6 mg/kg soil dw, OECD 222. Simon, 2021.

Eisenia andrei growth, mortality EC50: ≥ 189.6 mg/kg soil dw, OECD 222. Simon, 2021.

Terrestrial Plants

Most sensitive acute endpoint: Brassica rapa (turnip) EC50growth = 34.5 mg/kg soil dw, OECD 208. Simon, 2021. 

Most sensitive chronic endpoint: Solanum lycopersicum (tomato) EC10growth = 2.00 mg/kg soil dw, OECD 208. Simon, 2021.

Soil microorganisms

Soil microorganism nitrogen inhibition EC10 = 9.60 mg/kg soil dw, OECD 216. Simon, 2020.

Soil microorganism nitrogen inhibition EC50 = 18.3 mg/kg soil dw, OECD 216. Simon, 2020.

Additional information

A one-to-one read-across approach with correction for molecular weight has been used to derive endpoints for the target substance. The read-across was from benzotriazole (EC No.: 202-394-1) to sodium 1H-benzotriazolide (EC No. 239-269-6).  In line with ECHA guidance the reported endpoint values are those relevant to the target substance and have been corrected for molecular weight (ECHA How to prepare registration and PPORD dossiers, v10.0, 2021).  The only differences between the substances is the addition of a sodium salt in the target substance. However, at relevant environmental pH ca. 6-9, protonation will occur yielding the neutral form of the target substance (See Section 13.2 for more information). 

Three long-term tests with species representing different living and feeding conditions were available for the source substance. 

All tests were conducted in line with GLP and met the validity criteria for the respective OECD guidelines and were considered Klimisch 1. 

Of the 3 tested trophic levels, and species, terrestrial plants were found to be the most sensitive.  Specifically, Solanum lycopersicum (tomato) (EC10growth = 2.00 mg/kg soil dw).  The most sensitive (lowest EC/NOEC endpoint) will be used in the hazard/risk assessment.