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Link to relevant study record(s)

Description of key information

No study available. The relevant physico-chemical data are assessed in regard of toxicokinetics. (Assessment of the toxicokinetic behaviour of the substance to the extent that can be derived from the relevant available information, EC 2006/1907, Annex VII, 8.8.1)

Key value for chemical safety assessment

Bioaccumulation potential:
low bioaccumulation potential
Absorption rate - oral (%):
100
Absorption rate - dermal (%):
100
Absorption rate - inhalation (%):
10

Additional information

There is one study available for the structural analogue 1H-Benzotriazole on the metabolism. However, this study does not give sufficient information for this endpoint and is regarded as supporting study.

Physicochemical parameters used for toxicokinetic Endpoint summary:

Parameter

Value used for CSR

Molecular weight

141.11 g/mol

Melting point

Decomposition at 245 °C

Boiling point

Decomposition at 245 °C

Density

1.42 g/cm3(at 15 °C)

Vapour pressure

0.001 Pa (at 20 °C)

Partition coefficient n-octanol/water (log POW)

0.480 (at 25 °C)

Water solubility

> 10 g/L (at 25 °C) / 49.9 % w/w

pH

ca. 12

pKa

8.57 (at 25 °C)

Particle size

The substance is manufactured and marketed as aqueous solution

 

Based on these parameters, the bioaccumulation potential is judged as low (log POW< 4).

The pure substance is a solid with a low vapour pressure. It is manufactured and marketed as an aqueous solution. Based on this information the inhalative absorption is assumed to be 10 %. For dermal and oral Absorption rate 100 % are assumed by default.

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