Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
in vivo mammalian somatic cell study: cytogenicity / erythrocyte micronucleus
Remarks:
Type of genotoxicity: chromosome aberration
Adequacy of study:
other information

Data source

Reference
Reference Type:
publication
Title:
No information
Author:
OECD
Year:
2003
Bibliographic source:
SIDS Initial Assessment Report (2-dimethylaminoethyl acrylate)

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)
GLP compliance:
not specified
Type of assay:
micronucleus assay

Test material

Constituent 1
Chemical structure
Reference substance name:
2-(dimethylamino)ethyl acrylate
EC Number:
219-460-0
EC Name:
2-(dimethylamino)ethyl acrylate
Cas Number:
2439-35-2
Molecular formula:
C7H13NO2
IUPAC Name:
2-(dimethylamino)ethyl prop-2-enoate

Test animals

Species:
mouse
Strain:
other: Swiss OF1 / CO: OF1(IOPS Caw
Sex:
male/female

Administration / exposure

Route of administration:
intraperitoneal

Results and discussion

Test results
Sex:
male/female
Genotoxicity:
negative

Applicant's summary and conclusion