Registration Dossier

Administrative data

Endpoint:
in vivo mammalian somatic cell study: cytogenicity / erythrocyte micronucleus
Remarks:
Type of genotoxicity: chromosome aberration
Adequacy of study:
other information

Data source

Reference
Reference Type:
publication
Title:
No information
Author:
OECD
Year:
2003
Bibliographic source:
SIDS Initial Assessment Report (2-dimethylaminoethyl acrylate)

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)
GLP compliance:
not specified
Type of assay:
micronucleus assay

Test material

Constituent 1
Chemical structure
Reference substance name:
2-(dimethylamino)ethyl acrylate
EC Number:
219-460-0
EC Name:
2-(dimethylamino)ethyl acrylate
Cas Number:
2439-35-2
Molecular formula:
C7H13NO2
IUPAC Name:
2-(dimethylamino)ethyl acrylate

Test animals

Species:
mouse
Strain:
other: Swiss OF1 / CO: OF1(IOPS Caw
Sex:
male/female

Administration / exposure

Route of administration:
intraperitoneal

Results and discussion

Test results
Sex:
male/female
Genotoxicity:
negative

Applicant's summary and conclusion