Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 241-753-7 | CAS number: 17772-51-9
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
Description of key information
Within 28 days, a degradation rate of 0 % was determined. 3-hydroxy-2-(3-hydroxy-2-quinolyl)-1H-inden-1-one is considered to be "Not Readily Biodegradable". The reference compound sodium benzoate showed 88 % degradation after 14 days.
Key value for chemical safety assessment
- Biodegradation in water:
- under test conditions no biodegradation observed
Additional information
To test for its biodegradability potential of 3-hydroxy-2-(3-hydroxy-2-quinolyl)-1H-inden-1-one according to EU method C.4 -D “Manometric Respirometry Test“(2008) and the OECD guiedeline 301 F (adopted July 1992), the substance was incubated for 28 days in continuously stirrd 250 mL closed flask (in duplicate) in the dark with an inoculum originally collected from local, predominantly municipal wastewter treatment plant. In this assay, biodegradation was estimated by biological oxygen demand (BOD) over time. BOD was measured daily by a manometer. The incubation temperature was 22 ± 1 °C, pH was 7.4 - 8.0. The concentration of inoculum was 30 mg/L and the one of 3-hydroxy-2-(3-hydroxy-2-quinolyl)-1H-inden-1-one was a suspension of 100 mg/L. Degradation eas calculated by substracting the amount BOD in the negative (inoculum only) control from that in the substance or positive control at any given time point and divided by the chemical oxygen demand (COD) or thereotical oxygen demand (ThOD). The 28 -days degradation was 0 % and for the positive control (with reference substance) the biodegradation was 88 %. Therefore, 3-hydroxy-2-(3-hydroxy-2-quinolyl)-1H-inden-1-one is considered to be “Not Readily Biodegradable“.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
