Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 226-002-3 | CAS number: 5205-93-6
Partition coefficient
Administrative data
Link to relevant study record(s)
- Endpoint:
- partition coefficient
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2007-02-14 - 2007-03-30
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Remarks:
- OECD 107, non GLP, Study performed and documented equivalent to GLP standards. Study according to relevant guideline.
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 107 (Partition Coefficient (n-octanol / water), Shake Flask Method)
- Version / remarks:
- Directive 92/69/EEC, Official Journal L 383 A)
- GLP compliance:
- no
- Type of method:
- shake-flask method to: flask method
- Partition coefficient type:
- octanol-water
- Analytical method:
- high-performance liquid chromatography
- Type:
- log Pow
- Partition coefficient:
- 0.5
- Temp.:
- 24 °C
- pH:
- 10.6
- Conclusions:
- log Pow = 0.50 at room temperature (24 °C).
- Executive summary:
The log Pow is reported to be 0.50 at 24 °C measured according to OECD 107.
Reference
Test condition |
1 |
1 |
2 |
2 |
3 |
3 |
Concentration in the buffer phase [mg/ml] |
0.9208 |
0.9204 |
0.7776 |
0.7743 |
0.6699 |
0.6716 |
Mass in buffer phase [mg/ml] |
33.1474 |
33.1340 |
20.9951 |
20.9059 |
12.0585 |
12.0889 |
Concentration in octanol phase [mg] |
2.9553 |
2.8959 |
2.4155 |
2.4431 |
2.1140 |
2.1151 |
Actual total mass [mg] |
53.1952 |
52.1266 |
65.2187 |
65.9643 |
76.1023 |
76.1450 |
Calculated total mass [mg] |
86.3427 |
85.2606 |
86.2137 |
86.8702 |
88.1608 |
88.2329 |
| pH in aqueous phase | 10.63 |
10.64 |
10.62 |
|||
| Pow | 3.2095 | 3.1463 | 3.1064 | 3.1552 | 3.1557 | 3.1493 |
| Log Pow | 0.51 | 0.50 | 0.49 | 0.50 | 0.50 | 0.50 |
For all vessels there is good agreement between the actual and the calculated total mass. The log Pow values of the test item fall within a range of +/- units, thus the test is satisfactory
Description of key information
Log Kow (Pow) = 0.50 at 24 °C and pH 10.6 measured according to OECD 107 (Evonik Röhm Services, 2007)
Key value for chemical safety assessment
- Log Kow (Log Pow):
- 0.5
- at the temperature of:
- 20 °C
Additional information
OECD 107, Shake flask method
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
