Registration Dossier

Administrative data

Endpoint:
nanomaterial aspect ratio/shape
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2019
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
test procedure in accordance with national standard methods with acceptable restrictions

Data source

Reference
Reference Type:
other: unpublished study report
Title:
Unnamed
Year:
2019
Report date:
2019

Materials and methods

Principles of method if other than guideline:
Method selection according to Gaillard et al., Nanoscale Adv., 2019, 1, 781
GLP compliance:
no
Type of method:
transmission electron microscopy
Details on methods and data evaluation:
TEM image evaluation according to Verleysen et al., Materials 2019, 12, 2274; doi:10.3390/ma12142274
Sample Preparation:
Dispersion in ethanol; transfer to carbon-coated TEM-grids.

Test material

Constituent 1
Chemical structure
Reference substance name:
2,9-bis(p-methoxybenzyl)anthra[2,1,9-def:6,5,10-d'e'f']diisoquinoline-1,3,8,10(2H,9H)-tetrone
EC Number:
280-472-4
EC Name:
2,9-bis(p-methoxybenzyl)anthra[2,1,9-def:6,5,10-d'e'f']diisoquinoline-1,3,8,10(2H,9H)-tetrone
Cas Number:
83524-75-8
Molecular formula:
C40H26N2O6
IUPAC Name:
7,18-bis[(4-methoxyphenyl)methyl]-7,18-diazaheptacyclo[14.6.2.2²,⁵.0³,¹².0⁴,⁹.0¹³,²³.0²⁰,²⁴]hexacosa-1(22),2,4,9,11,13(23),14,16(24),20,25-decaene-6,8,17,19-tetrone
Test material form:
solid: nanoform

Data gathering

Instruments:
Thermo-Fisher Osiris 200kV
Calibration:
no data
Reproducibility:
no data

Results and discussion

Shape description
Key result
Shape:
rod
Remarks on result:
other: The material is assigned to the “elongated” shape category.
Aspect ratio
Key result
x Dimension:
3.2
St. dev.:
2.1
y Dimension:
1
Remarks on result:
other: median (D50)

Any other information on results incl. tables

The number-based concentration of particles with sizes below 100 nm (smallest feret diameter) is 66%. The median (D50) of the particle size is 83 nm.

The material is therefore classified as “nano” according to the definition of nanomaterial 2011/696/EU.

Applicant's summary and conclusion

Conclusions:
The particles have a median aspect ratio of 3,2:1.
The shape is “rod”. The material is assigned to the “elongated” shape category.