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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Short-term toxicity to fish

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Administrative data

Link to relevant study record(s)

Description of key information

LC50>180 mg/l

Key value for chemical safety assessment

Fresh water fish

Fresh water fish
Effect concentration:
180 mg/L

Additional information

The available literature study on Direct Red 81 was used as a key study and an LC50 value of > 180 mg/l was derived.

In the Clariant study of 2002 a similar substance was tested on freshwater fish at the limit dose of 100 mg/L. At this concentration no adverse effects were observed, so an LC50 value >100 mg/L was derived.

In Synthesia study of 2001 another similar substance was tested and based on the test conditions an LC50 value of > 100 mg/l was derived.

The conclusion that DRED81 is not toxic to fish is confirmed by the key study and by the supporting studies available.