Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Direct observations: clinical cases, poisoning incidents and other

Currently viewing:

Administrative data

Endpoint:
direct observations: clinical cases, poisoning incidents and other
Type of information:
migrated information: read-across from supporting substance (structural analogue or surrogate)
Adequacy of study:
supporting study
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: Secondary literature

Data source

Reference
Reference Type:
secondary source
Title:
Patty's Toxicology
Author:
Bingham E, et al.
Year:
2003
Bibliographic source:
Bingham E (ed.) Patty's Toxicology. Aliphatic Carboxylic Acids, Saturated. John Wiley & Sons, Inc. Fifth Edition, volume 5. 694-777. New York.

Materials and methods

Study type:
other: occupational study
Endpoint addressed:
other: inhalation
Test guideline
Qualifier:
no guideline available
GLP compliance:
not specified

Test material

Constituent 1
Reference substance name:
Formic acid
EC Number:
200-579-1
EC Name:
Formic acid
Cas Number:
64-18-6
IUPAC Name:
formic acid
Test material form:
not specified

Method

Subjects:
workers in a textile plant
Route of exposure:
inhalation
Reason of exposure:
unintentional, occupational
Exposure assessment:
not specified

Results and discussion

Clinical signs:
Workers exposed to formic acid in a textile plant reported nausea from vapor concentrations around 15ppm.

Applicant's summary and conclusion

Conclusions:
Formic acid can cause nausea if inhaled at concentration around 15ppm.