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Solubility in organic solvents / fat solubility

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Endpoint:
solubility in organic solvents / fat solubility
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
test procedure in accordance with generally accepted scientific standards and described in sufficient detail
Justification for type of information:
Data is from experimental study report
Qualifier:
according to guideline
Guideline:
other: as mentioned below
Principles of method if other than guideline:
Weight of the chemical substance (fat) to dissolve in Organic Solvent to form a homogeneous solution of the solute in the solvent.
GLP compliance:
no
Other quality assurance:
ISO/IEC 17025 (General requirements for the competence of testing and calibration laboratories)
Key result
Medium:
methanol
Solubility:
4 100 mg/L
Temp.:
23 °C
Conclusions:
The experimental value of solubility of test chemical in methanol at temperature of 23 deg C was determined to be 4100 mg/L indicating that it is soluble in methanol.
Executive summary:

The experimental value of solubility of test chemical in methanol at temperature of 23 deg C was determined to be 4100 mg/L indicating that it is soluble in methanol.

Endpoint:
solubility in organic solvents / fat solubility
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
test procedure in accordance with generally accepted scientific standards and described in sufficient detail
Justification for type of information:
Data is from experimental study report
Qualifier:
according to guideline
Guideline:
other: as mentioned below
Principles of method if other than guideline:
Weight of the chemical substance (fat) to dissolve in Organic Solvent to form a homogeneous solution of the solute in the solvent.
GLP compliance:
no
Other quality assurance:
ISO/IEC 17025 (General requirements for the competence of testing and calibration laboratories)
Key result
Medium:
other: Petroleum ether
Solubility:
880 mg/L
Temp.:
23 °C
Conclusions:
The experimental value of solubility of test chemical in Petroleum ether at temperature of 23 deg C was determined to be 880mg/L. This value indicates that it is moderately soluble in petroleum ether.
Executive summary:

The experimental value of solubility of test chemical in Petroleum ether at temperature of 23 deg C was determined to be 880mg/L. This value indicates that it is moderately soluble in petroleum ether.

Description of key information

Gravimetric method was used to determine the solubility of the substance in organic solvent. The experimental value of solubility of test chemical in methanol at temperature of 23 deg C was determined to be 4100 mg/L indicating that it is soluble in methanol.

Using the Soxhlet/Solvent extraction method, solubility of test chemical in Petroleum ether at temperature of 23 deg C was determined to be 880mg/L. This value indicates that it is moderately soluble in petroleum ether.

Key value for chemical safety assessment

Solubility in organic solvents at 20°C:
3 565.21 mg/L

Additional information

Gravimetric method was used to determine the solubility of the substance in organic solvent. The experimental value of solubility of test chemical in methanol at temperature of 23 deg C was determined to be 4100 mg/L indicating that it is soluble in methanol.

The solubility value of test chemical in methanol at 20 degC is equivalent to a value of 3565.21 mg/L.

Using the Soxhlet/Solvent extraction method,solubility of test chemical in Petroleum ether at temperature of 23 deg C was determined to be 880mg/L. This value indicates that it is moderately soluble in petroleum ether.