Lactonitrile

Toxicity to aquatic algae and cyanobacteria

Administrative data

Endpoint:

toxicity to aquatic algae and cyanobacteria

Type of information:

experimental study

Adequacy of study:

key study

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

other: Guideline study with acceptable restrictions (non-GLP)

Data source

Reference

Reference Type:

secondary source

Title:

Unnamed

Year:

1992

Report date:

1992

Materials and methods

Test guideline

Qualifier:

according to guideline

Guideline:

OECD Guideline 201 (Alga, Growth Inhibition Test)

GLP compliance:

no

Test material

Test material information

Constituent 1

Reference substance name:

Lactonitrile

EC Number:

201-163-2

EC Name:

Lactonitrile

Cas Number:

78-97-7

Molecular formula:

C3H5NO

IUPAC Name:

2-hydroxypropanenitrile

Details on test material:

2-Hydroxypropanenitrile
Purity: 92.3 %

Sampling and analysis

Analytical monitoring:

no

Test organisms

Test organisms (species):

Raphidocelis subcapitata (previous names: Pseudokirchneriella subcapitata, Selenastrum capricornutum)

Study design

Limit test:

no

Results and discussion

Effect concentrations

Effect concentrations 1

Duration:

72 h

Dose descriptor:

EC50

Effect conc.:

0.14 mg/L

Basis for effect:

biomass

Effect concentrations 2

Duration:

72 h

Dose descriptor:

NOEC

Effect conc.:

<= 0.048 mg/L

Basis for effect:

biomass

Any other information on results incl. tables

RS-Freetext:
NOEC =< 0.048 mg/L (p < 0.05)