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Biodegradation-Screening:

In a valid OECD 301B test a mean degradation rate after 28 d of 10-20% CO2/ThCO2 was recorded. Acccording to the test result the substance is not biodegradable under the chosen conditions.

 

In the Guidance on Information requirements and chemical safety assessment R11 PBT, additional assessment criteria are indicated whether a substance may potentially fulfil criteria for PBT. The two recommended models Biowin 2 (non linear model prediction) and Biowin 3 (ultimate biodegradation time) within the complete Biowin-family (Biowin1-6) have been used to screen the test item for criteria of persistence.

 

Additional simulation with QSAR using the Biowin family Biowin 1-6 predicts contradicting results indicating that the substance will biodegradate fast. The non -linear model of Biowin 2 and the ultimate biodegradation time of Biowin 3 calculate values of 0.66 and 2.96, respectively. Furthermore, the Miti non-linear model predicting of Biowin 6 indictes a fast biodegradation (>0.6). Based on the screening models there is no indication that the test item is persistent.

Biodegradation in water, sediment and soil: simulation tests

Quaternary ammonium compounds, Amines, tri-C8-10-alkyl is used as a catalyst in industrial applications where it is regenerated after use and is not intentionally discharged. Furthermore, the substance is used only in industrial application where risk management measures are installed to avoid any contamination of the environment. Simulation testing in water can further be disregarded as the substance is highly insoluble in water (water solubility < 3.4E-06 mg/l (based on Log KOW (WSKow v.1.42)) to < 9.0E-09 mg/l (based on estimates of fragments WatSol v. 1.01)).

Sediment siumlation testing does not need to be conducted if, in accordance with Column 2 adaptation statement of REACH Annex IX, information requirement 9.2.1.4, direct or indirect exposure to sediment is unlikely.

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