Registration Dossier
Registration Dossier
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EC number: 423-460-8 | CAS number: 3508-98-3 SALICYNALVA
Hydrolysis
Administrative data
Link to relevant study record(s)
Description of key information
Salicynalva possesses half-life times in water of 25.9 days at pH 4, 15.4 days at pH 7 and 4.7 days at pH 9 at 25°C.
Key value for chemical safety assessment
- Half-life for hydrolysis:
- 15.4 d
- at the temperature of:
- 25 °C
Additional information
The hydrolysis of the substance has been tested using a protocol similar to OECD TG 111 and in compliance with EU Method C7. Hydrolysis was evaluated at 50°C in aqueous solutions at pH 4, 7 and 9. The starting concentration of Salicynalva (purity > 95%) was circa 15 mg/L. At each time point, including 0 hours, 2.4 hours and 5 days, an aliquot of test solution was diluted with mobile phase and the concentration of the substance determined by HPLC analysis. Under the preliminary test condition, the substance was found to undergo hydrolysis at pH 4, 7 and 9, which indicated a half-life of between 1 day and 1 year at 25 ºC and therefore a full study was carried out. Under the test conditions in the first test at 50°C, the substance was found to undergo a pseudo first order reaction at pH 4, 7 and 9 and therefore the final test was performed at 60 and 70°C. The results in this test showed that Salicynalva possesses half-life times in water of 25.9 days at pH4, 15.4 days at pH 7 and 4.7 days at pH 9 at 25°C.
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