Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 237-537-7 | CAS number: 13827-02-6
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
The 96-h LC50 value for potassium trifluorozincate in zebra fish (Brachydanio rerio) of >4.6 mg/L, which is equivalent to >1.87 mg zinc/L and >1.63 mg fluoride/L based on the molecular weight fractions for zinc and fluoride, respectively. The 96-h LC50 in Gobiocypris rarus was 9.2 mg/L (95% CL 7.07 to 11.7 mg/L).
Key value for chemical safety assessment
Additional information
Two reliable short-term toxicity studies in fish are available for potassium trifluorozincate.
A GLP-compliant OECD 203 guideline study with zebrafish (Danio rerio) was conducted as limit test. In this test, 7 fish were exposed for 96 hours under static conditions to a nominal concentration of 4.6 mg/L (based on threshold approach). The test concentrations were analytically verified and were within ±20% of the nominal concentration. Therefore, biological effect concentrations are expressed based on the nominal concentrations. There was no mortality in either the control or the test item treatment during the exposure period. No non-lethal effects were noted. Based on these findings the 96-h LC50 was determined at >4.6 mg/L.
As potassium trifluorozincate in water rapidly dissociates into its various ions, it is these ions that are expected to be present in the environment and which will therefore be assessed. Therefore, effect values for potassium trifluorozincate are also expressed as zinc and fluoride based on their respective molecular weight fractions (potassium is not assessed because of its environmental abundance and low toxicity). This leads to 96 -h LC50 values of >1.87 mg zinc/L and >1.63 mg fluoride/L. A second GLP-compliant OECD 203 guideline study with Gobiocypris rarus was conducted as part of a new chemical substance notification in China. In this static test, 7 fish were exposed for 96 hours to six treatment groups and a control group. The nominal concentrations of the treatment groups were 5, 8, 12, 18, 27 and 40 mg/L. No mortality occurred in the control during the test and the dissolved oxygen concentration was greater than 60% of the air saturation value throughout the test duration. Hence, the test was considered to be valid.During the test, the measured concentrations of Fluoride varied less than 20% of their initial measured concentrations. The 96h LC50 value (based on the nominal concentrations) for the test substance to Gobiocypris rarus was 9.2 mg/L (95% CI of 7.07 to 11.7 mg/L).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
