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Ecotoxicological information

Short-term toxicity to fish

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Description of key information

The lethal concentration (LC50) value of 2-aminobenzenesulphonic acid in fish [Pimephales promelas] in a 96 hr study on mortality effect was estimated to be 193.4513 mg/L . Thus,considering the CLP Criteria for aquatic classification of the substance , it is concluded that 2-aminobenzenesulphonic acid  does not exhibit short term toxicity to fish [Pimephales promelas].

Key value for chemical safety assessment

Fresh water fish

Fresh water fish
Effect concentration:
193.451 mg/L

Additional information

No. of studies were reviewed for Short-term toxicity to fish from reliable sources having Klimisch rating 2 and 4.

The summary of the results are presented below  

Sr.No

Endpoint

Effect values

Basis for effects

Duration

Species

Sources

1.

LC50

193.451mg/L

Mortality

96 hrs.

Pimephales promelas

Predicted data from QSAR for target CAS:88-21-1

2.

LC50

100.4 mg/L

Mortality

96 hrs.

Pimephales promelas

Experimental data from Journal of Hydrology for read across CAS:127-57-3

3.

LC50

480 mg/L

Mortality

48 hrs.

Oryzias latipes

Experimental data from MITI Japan for read across CAS:88-44-8

 

Based on the studies summarized in the above table for the target substance 2-aminobenzenesulphonic acid and the read across substance, the endpoint value was found to vary between LC50 = 100.4 mg/L to 193.451mg/L in a 96 hrs and at 48 hrs. LC50 =480 mg/L; on the basis of mortality effect. Based on the above weight of evidence values, it is concluded that the test substance dose not qualifies for the aquatic toxicity.