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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Short-term toxicity to fish

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Administrative data

Link to relevant study record(s)

Description of key information

The lethal concentration (LC50) value of 2-aminobenzenesulphonic acid in fish [Pimephales promelas] in a 96 hr study on mortality effect was estimated to be 193.4513 mg/L . Thus,considering the CLP Criteria for aquatic classification of the substance , it is concluded that 2-aminobenzenesulphonic acid  does not exhibit short term toxicity to fish [Pimephales promelas].

Key value for chemical safety assessment

Fresh water fish

Fresh water fish
Effect concentration:
193.451 mg/L

Additional information

No. of studies were reviewed for Short-term toxicity to fish from reliable sources having Klimisch rating 2 and 4.

The summary of the results are presented below  



Effect values

Basis for effects








96 hrs.

Pimephales promelas

Predicted data from QSAR for target CAS:88-21-1



100.4 mg/L


96 hrs.

Pimephales promelas

Experimental data from Journal of Hydrology for read across CAS:127-57-3



480 mg/L


48 hrs.

Oryzias latipes

Experimental data from MITI Japan for read across CAS:88-44-8


Based on the studies summarized in the above table for the target substance 2-aminobenzenesulphonic acid and the read across substance, the endpoint value was found to vary between LC50 = 100.4 mg/L to 193.451mg/L in a 96 hrs and at 48 hrs. LC50 =480 mg/L; on the basis of mortality effect. Based on the above weight of evidence values, it is concluded that the test substance dose not qualifies for the aquatic toxicity.