Registration Dossier
Registration Dossier
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EC number: 204-427-5 | CAS number: 120-80-9
Biological effects monitoring
Administrative data
- Endpoint:
- biological effects monitoring
- Type of information:
- experimental study
- Adequacy of study:
- disregarded due to major methodological deficiencies
- Reliability:
- 3 (not reliable)
- Rationale for reliability incl. deficiencies:
- significant methodological deficiencies
- Remarks:
- Test not enough described. The sensitivity of this test seems to be low compared to results from other similar tests.
Data source
Reference
- Reference Type:
- publication
- Title:
- Whole cell biosensors - electrochemical and optical approaches to ecotoxicity testing
- Author:
- Bentley A., Atkinson A., Jezek J., Rawson D.M.
- Year:
- 2 001
- Bibliographic source:
- Toxicology in Vitro, 15, 469-475.
Materials and methods
- Principles of method if other than guideline:
- Luminescent reporter genes were used to determine changes in the metabolic status of the bluegill sunfish (BF-2) epithelial cells.
- GLP compliance:
- not specified
- Type of study / information:
- In vitro cytotoxicity effects using fish modified BF-2 cells
Test material
- Reference substance name:
- Pyrocatechol
- EC Number:
- 204-427-5
- EC Name:
- Pyrocatechol
- Cas Number:
- 120-80-9
- Molecular formula:
- C6H6O2
- IUPAC Name:
- pyrocatechol
- Details on test material:
- No data.
Constituent 1
Results and discussion
Any other information on results incl. tables
The EC50 (30 min) using BF-2/luc1 cells was 761 mg/L (6.91 mM).
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
