Registration Dossier
Registration Dossier
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EC number: 401-210-9 | CAS number: 83708-14-9 BEHENYLKETENDIMER; HERCULES PMC D-532; PMC D-532
Repeated dose toxicity: oral
Administrative data
- Endpoint:
- repeated dose toxicity: oral
- Data waiving:
- other justification
- Justification for data waiving:
- other:
Data source
Reference
- Reference Type:
- other: Body responsible for the test
- Title:
- Unnamed
Materials and methods
- Limit test:
- no
Test material
- Reference substance name:
- 3-icosyl-4-henicosylidene-2-oxetanone
- EC Number:
- 401-210-9
- EC Name:
- 3-icosyl-4-henicosylidene-2-oxetanone
- Cas Number:
- 83708-14-9
- Molecular formula:
- C44H84 O2
- IUPAC Name:
- (4Z)-4-henicosylidene-3-icosyloxetan-2-one
Constituent 1
Test animals
- Species:
- other: Rat, CD (SD) BR strains, males and females
Administration / exposure
- Route of administration:
- oral: unspecified
- Duration of treatment / exposure:
- Test duration: 90 days
- Frequency of treatment:
- Dosing regime: 7 days/week
- No. of animals per sex per dose:
- Male: 20 animals at CA 0 mg/kg bw/day
Male: 20 animals at CA 20 mg/kg bw/day
Male: 20 animals at CA 200 mg/kg bw/day
Male: 20 animals at CA 2000 mg/kg bw/day
Female: 20 animals at CA 0 mg/kg bw/day
Female: 20 animals at CA 20 mg/kg bw/day
Female: 20 animals at CA 200 mg/kg bw/day
Female: 20 animals at CA 2000 mg/kg bw/day
Results and discussion
Effect levels
open allclose all
- Dose descriptor:
- NOAEL
- Effect level:
- ca. 20 mg/kg bw/day (nominal)
- Basis for effect level:
- other: original NCD unit is mg/kg/day.
- Dose descriptor:
- NOEL
- Effect level:
- ca. 20 mg/kg bw/day (nominal)
- Basis for effect level:
- other: original NCD unit is mg/kg/day.
Target system / organ toxicity
- Critical effects observed:
- not specified
Applicant's summary and conclusion
- Conclusions:
- Test results did not lead to Substance classification
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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