Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 202-548-8 | CAS number: 96-97-9
Bioaccumulation: aquatic / sediment
Administrative data
Link to relevant study record(s)
Description of key information
Bioaccumulation is the process by which the chemical concentration in an aquatic organism achieves a level that exceeds that in the water, as a result of chemical uptake through all possible routes of exposure. The relationship between bioaccumulation and bio-concentration is that, chemicals that have the potential to bioconcentrate also have the potential to bioaccumulate. Bioaccumulation is closely related to the Bioconcentration factor (BCF).
The estimated bioconcentration factor (BCF) for 5-nitrosalicylic acid is 3.2, which does not exceeds the EPA bioconcentration criteria (>= 1,000). Thus, it is concluded that 5-nitrosalicylic acid is not expected to bioaccumulate in the food chain because it does not exceed the BCF criteria.
Key value for chemical safety assessment
- BCF (aquatic species):
- 3.2 dimensionless
Additional information
No. of studies of target substance 5-nitrosalicylic acid reviewed for bioaccumulation from reliable sources having Klimisch rating 2.
The summary of the results are presented below
Sr.No |
Endpoint |
Value |
result |
Sources |
1 |
BCF |
3.2 |
Non-bioaccumulative |
Predicted data from PBT profiler |
2 |
BCF |
2.897 L/Kg |
Non-bioaccumulative |
Predicted data from QSAR |
3 |
BCF |
3.1622 L/Kg |
Non-bioaccumulative |
Predicted data from Vega QSAR |
By applying weight of evidence approach the target chemical 5-nitrosalicylic acid found to be non bioaccumulative with BCF value2.897 L/Kg3.2 L/Kg whichis not expected to bioaccumulate in the food chain because it does not exceed the BCF criteria.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
