Registration Dossier

Ecotoxicological information

Endpoint summary

Administrative data

Description of key information

Additional information

AQUATIC TOXICITY

 

Short-term toxicity to fish

 

Two key studies and eight supporting studies showed that the nominal LC50 value is above 100 mg/L. In the both key studies (Danio rerio) a NOEC of 100 mg/L is reported. Four supporting studies were performed to assess the acute toxicity of the test item to Salmo gairdneri (Onchorhynchus mykiss). LC50 values from 125 to 200 mg/L nominal are reported. Four supporting studies were performed to assess the acute toxicity of the test item to Cyprinus carpio. LC50 values from 112 to 164 mg/l nominal are reported. In all supporting studies the died fishes showed a milky discoloration of the skin and pale red gills edges. These findings probably based on the high acidity of the substance and the low pH value.

 

Log-term toxicity to fish

 

Waiving according to "column 2" in Annex IX of REGULATION (EC) No 1907/2006 (CSA does not indicate need for further investigations)

 

Short-term toxicity to daphnia

 

Two key studies and one supporting study shows that the nominal EC50 value for freshwater invertebrates is above 100 mg ai /L. In one key study and in the supporting study a NOEC of 100 mg ai /L is reported. In the two highest concentrations (140 and 200 mg/L) in the supporting study effects have occurred. In both concentrations the pH was below 6 (140 mg/L = 5.5 and 200 mg/L =3.6). Therefore it can not be excluded, that the effects based on the low pH value only. The values will not be used for chemical safety assessment.

 

Long-term toxicity to daphnia

 

Waiving according to "column 2" in Annex IX of REGULATION (EC) No 1907/2006 (CSA does not indicate need for further investigations)

 

Toxicity to aquatic algae

 

Slight toxic effects reported in two studies were caused by the low pH-value. Replicates with the test item concentration of 100 mg/L adjusted to pH 7.9 showed no toxic effects. The pH neutralization reflects the actually existing environmental conditions in the buffered aquatic systems. Therefore it can be concluded that the test item has no effect on algae.

 

Toxicity to microorganisms

Two studies were performed to assess the effect of the test item on the respiration of activated sewage sludge. The effect of the test item on the respiration of activated sewage sludge gave a 3-Hour EC50/IC50 of >1000 mg/l (nominal) and > 100 mg/L (nominal). The test item was found to be non-toxic to waste-water bacteria in both studies.