Registration Dossier
Registration Dossier
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EC number: 425-660-0 | CAS number: 165101-57-5
Bioaccumulation: aquatic / sediment
Administrative data
Link to relevant study record(s)
- Endpoint:
- bioaccumulation in aquatic species: fish
- Data waiving:
- study scientifically not necessary / other information available
- Justification for data waiving:
- other:
Reference
Description of key information
Not applicable
Key value for chemical safety assessment
Additional information
The performance of a test for bioaccumulation in aquatic species, preferably fish, is scientifically unjustified.
REACH Regulation (EC) No 1907/2006, Annex IX, Sect. 9.3.2, Col. 2, states as follows:
“9.3.2 The study need not be conducted if:
- the substance has a low potential for bioaccumulation (for instance a log Kow <= 3) and/or a low potential to cross biological membranes, or
- direct and indirect exposure of the aquatic environment is unlikely.”
Direct and indirect exposure of the test item to water is highly unlikely. Due to the unstable nature of the test substance, it can be assumed that upon contact with water and organic matter, the test item undergoes rapid degradation resulting in the formation of respective hydrolysis degradation products. Therefore, the test substance was considered to have no bioaccumulation potential. In addition, the test substance has log Pow of 4.2 and a low log Koc of 3.15, showing together with hydrolysis data, that the substance will not be available in the environment for long times. Using EPIWIN 4.11 a BCF of 17.57 L/Kg wwt was calculated indicating no potential for bioaccumulation.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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