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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Environmental fate & pathways

Bioaccumulation: aquatic / sediment

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Administrative data

Link to relevant study record(s)

Reference
Endpoint:
bioaccumulation in aquatic species: fish
Type of information:
experimental study
Adequacy of study:
key study
Study period:
1977
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
comparable to guideline study with acceptable restrictions
Qualifier:
equivalent or similar to guideline
Guideline:
other: MITI (guideline Nr. not specified)
GLP compliance:
no
Specific details on test material used for the study:
None
Radiolabelling:
not specified
Details on sampling:
no data
Vehicle:
not specified
Details on preparation of test solutions, spiked fish food or sediment:
no data
Test organisms (species):
Cyprinus carpio
Details on test organisms:
TEST ORGANISM
- Common name: common carp
Route of exposure:
aqueous
Test type:
not specified
Water / sediment media type:
not specified
Remarks:
freshwater
Total exposure / uptake duration:
8 wk
Hardness:
no data
Test temperature:
no data
pH:
no data
Dissolved oxygen:
no data
TOC:
no data
Salinity:
no data
Details on test conditions:
no data
Nominal and measured concentrations:
Nominal: 0, 0.01 and 0.001 ppm = 1 and 10 µg/L
Reference substance (positive control):
no
Conc. / dose:
0.001 other: ppm
Type:
BCF
Value:
< 2 143 L/kg
Remarks on result:
other: Conc.in environment / dose:1 ppb
Conc. / dose:
0.01 other: ppm
Type:
other: AF
Value:
< 214 L/kg
Remarks on result:
other: Conc.in environment / dose:10 ppb
Details on kinetic parameters:
no data
Metabolites:
no data
Results with reference substance (positive control):
no data
Details on results:
no data
Reported statistics:
no data

Table 1: Results at 1 µg/L exposure concentration
Time Concentration in water (µg/L) Concentration in fish (µg/kg) BCF*
Week 1 < 36 < 2143 < 2143
Week 2 < 36 < 2143 < 2143
Week 3 < 36 < 2143 < 2143
Week 4 < 36 < 2143 < 2143
Week 5 < 36 < 2143 < 2143
Week 6 < 36 < 2143 < 2143
Week 7 < 36 < 2143 < 2143
Week 8 < 36 < 2143 < 2143
* Calculated using the nominal concentration of 1 µg/L
Table 2: Results at 10 µg/L exposure concentration
Time Concentration in water (µg/L) Concentration in fish (µg/kg) BCF*
Week 1 < 36 < 2143 < 214
Week 2 < 36 < 2143 < 214
Week 3 < 36 < 2143 < 214
Week 4 < 36 < 2143 < 214
Week 5 < 36 < 2143 < 214
Week 6 < 36 < 2143 < 214
Week 7 < 36 < 2143 < 214
Week 8 < 36 < 2143 < 214
* Calculated using the nominal concentration of 10 µg/L
Validity criteria fulfilled:
no
Conclusions:
Under the conditions of a MITI test, the bioconcentration factor (= concentration in fish / concentration in water) in carp at 1 µg/L was <2143 L/kg. At 10 µg/L, it was <214 L/kg. These results suggest that the test substance has a low bioconcentration potential in fish.
Executive summary:

A study was conducted to assess the bioconcentration potential of the test substance (of ca. 89 % purity) in common carp (Cyprinus carpio) according to the MITI method. Fish were exposed at 1 and 10 ppb (= 1 and 10 µg/L) for 8 weeks. Average concentrations in water and fish were recorded weekly. At 1 µg/L, the bioconcentration factor (= concentration in fish / concentration in water) was <2143 L/kg. At 10 µg/L, it was <214 L/kg. These results suggest that the test substance has a low bioconcentration potential in fish.

Description of key information

A study was conducted to assess the bioconcentration potential of the test substance (of ca. 89 % purity) in common carp (Cyprinus carpio) according to the MITI method.

Fish were exposed at 1 and 10 ppb (= 1 and 10 µg/L) for 8 weeks. Average concentrations in water and fish were recorded weekly. At 1 µg/L, the bioconcentration factor (= concentration in fish / concentration in water) was <2143 L/kg. At 10 µg/L, it was <214 L/kg. These results suggest that the test substance has a low bioconcentration potential in fish.

Key value for chemical safety assessment

BCF (aquatic species):
214 L/kg ww

Additional information