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Environmental fate & pathways

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The bioaccumulation and depuration of the test item were studied with 14C-labeled test substance in rainbow trout maintained in a continous flow-through system in accordance with OECD guideline 305. Mean bioconcentration factors at steady-state were in the range 66 - 179. Accumulation of radioactive residues was in the order edible < whole-fish < non-edible tissues and well below 1000, therefore the test item is not considered to be bioaccumulative. Elimination of the test item during the depuration phase was relatively slow. Kinetic analysis indicated that approximately 90% of the radioactive residues were eliminated in 36 - 44 days.