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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Endpoint summary

Administrative data

Description of key information

Additional information

No short-term terrestrial test data is available forN-[2-(piperazin-1-yl)ethyl]C18-insaturated-alkylamide. One long term earthworm test has been performed with N-[2-(piperazin-1-yl)ethyl]C18-insaturated-alkylamideresulting in a NOEC of 940 mg a. i./kg dw.

A study by Witte, B. 2010 was carried out to determine the toxicity of fatty acids, C18 reaction products with 1 -piperazineethanamine on the reproduction and growth of earthworms.

All study validity criteria were met. No mortality was observed in any treatment group. The body weight change of the earthworms after 4 weeks exposure for Fatty acids, C16-18, reaction products with 1-piperazineethanamine was not statistically significant different compared to the control up to and including the highest test concentration of 1000 mg test /kg soil dry weight (or 940 mg a.i./kg soil dry weight)

The reproduction rates after 8 weeks exposure to Fatty acids, C16-18, reaction products with 1-piperazineethanamine were not significantly different compared to the control up to and including the highest test concentration of 1000 mg test item/kg soil (Dunnett's t-test,α= 0.05). No behavioural abnormalities were observed in any of the treatment groups.

There are no other data available for characterizing the effects of N-[2-(piperazin-1-yl) ethyl]C18-insaturated-alkylamide on soil organisms. N-[2 -(piperazin-1 -yl) ethyl]C18 -insaturated-alkylamide sorbs strongly to soil and the bioavailable fraction is quickly degraded to form 1 aminoethylpiperazine. In addition, the test substance was observed to be not harmful to sludge micro-organisms. Further tests on soil micro-organisms do therefore not need to be conducted if no concern is indicated for the terrestrial compartment based on one long-term test result.