Registration Dossier
Registration Dossier
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EC number: 629-767-5 | CAS number: 1228186-18-2
Endpoint summary
Administrative data
Description of key information
Additional information
No short-term terrestrial test data is available forN-[2-(piperazin-1-yl)ethyl]C18-insaturated-alkylamide. One long term earthworm test has been performed with N-[2-(piperazin-1-yl)ethyl]C18-insaturated-alkylamideresulting in a NOEC of 940 mg a. i./kg dw.
A study by Witte, B. 2010 was carried out to determine the toxicity of fatty acids, C18 reaction products with 1 -piperazineethanamine on the reproduction and growth of earthworms.
All study validity criteria were met. No mortality was observed in any treatment group. The body weight change of the earthworms after 4 weeks exposure for Fatty acids, C16-18, reaction products with 1-piperazineethanamine was not statistically significant different compared to the control up to and including the highest test concentration of 1000 mg test /kg soil dry weight (or 940 mg a.i./kg soil dry weight)
The reproduction rates after 8 weeks exposure to Fatty acids, C16-18, reaction products with 1-piperazineethanamine were not significantly different compared to the control up to and including the highest test concentration of 1000 mg test item/kg soil (Dunnett's t-test,α= 0.05). No behavioural abnormalities were observed in any of the treatment groups.
There are no other data available for characterizing the effects of N-[2-(piperazin-1-yl) ethyl]C18-insaturated-alkylamide on soil organisms. N-[2 -(piperazin-1 -yl) ethyl]C18 -insaturated-alkylamide sorbs strongly to soil and the bioavailable fraction is quickly degraded to form 1 aminoethylpiperazine. In addition, the test substance was observed to be not harmful to sludge micro-organisms. Further tests on soil micro-organisms do therefore not need to be conducted if no concern is indicated for the terrestrial compartment based on one long-term test result.
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