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EC number: 700-066-7 | CAS number: 1472633-72-9
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
The reference substance hydrolyses within less than an hour to its hydrolysis products; Boric acid and glycerol. Therefore, conducting an acute toxicity study on the reference substance is not feasible.
Key value for chemical safety assessment
Additional information
The reference substance hydrolyses within less than an hour to its hydrolysis products; Boric acid and glycerol. Therefore, conducting a acute toxicity to aquatic invertebrates (daphnia) study on the reference substance is not feasible. If a study were conducted it would give a result representative of the hydrolysis products mentioned above.
The acute toxicity of the hydrolysis products, boric acid and glycerol has been assessed.
Boric acid
Study data on boric acid has been provided for the following endpoints:
- Toxicity to soil macroorganisms (see earthworm toxicity study)
- Sediment toxicity (see Toxicity test with the midge larva Chironomus riparius using spiked sediment.)
The results of these studies show boric acid to be of very low toxicity to soil and sediment invertebrates. This indicates that boric acid would also be of low toxicity to aquatic invertebrates, such as Daphnia.
Refer to section 13, Ecotoxicological expert report (BAGE: Evaluation of Environmental Fate and Ecotoxicity Properties) for further details of the evalaution of ecotoxicological properties of boric acid. The available data indicates boric acid is of low toxicity to aquatic invertebrates.
Glycerol
Glycerol is the other hydrolysis product of the reference substance, BAGE. It is not classified for the environment according to CLP or DSD.
Available data (see section 13) suggests that glycerol is of low toxicity to invertebrates.
Refer to section 13, Ecotoxicological expert report (BAGE: Evaluation of Environmental Fate and Ecotoxicity Properties) for further details of the evalaution of ecotoxicological properties of gycerol.
Supporting data
As the reference substance hydrolyses within less than an hour to its hydrolysis products; Boric acid and glycerol it was not feasible to conduct an algal inhibition study on the reference substance, as the result will be representative of the hydrolysis products Boric acid and glycerol.
A QSAR prediction has therefore been made for the reference substance (BAGE), using EPIWIN program ECOSAR (v0.99h).
The following predicitons for BAGE were made:
Daphnia: 48 hour EC50: 1.13 x 1011 mg/L
Daphnia: 16-day EC50: 8.84 x 107 mg/L
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