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Ecotoxicological information

Short-term toxicity to fish

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Link to relevant study record(s)

Reference
Endpoint:
short-term toxicity to fish
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Qualifier:
according to guideline
Guideline:
OECD Guideline 203 (Fish, Acute Toxicity Test)
Version / remarks:
92/69/EEC, C1 (Limit test)
GLP compliance:
yes
Analytical monitoring:
yes
Remarks:
measured concentrations over the first and last 24 hours of the exposure period were 101 - 89.4 mg/l and 105 - 104 mg/l respectively
Details on test solutions:
Identity and concentration of auxiliary solvent for dispersal: None.
Test organisms (species):
Oncorhynchus mykiss (previous name: Salmo gairdneri)
Test type:
static
Limit test:
yes
Total exposure duration:
96 h
Hardness:

CA 170 mg CaCO3/L
Nominal and measured concentrations:
nominal: 100 mg/L

measured concentrations over the first and last 24 hours of the exposure period were 101 - 89.4 mg/l and 105 - 104 mg/l respectively
Duration:
96 h
Dose descriptor:
NOEC
Effect conc.:
ca. 100 mg/L
Nominal / measured:
nominal
Basis for effect:
mortality (fish)
Key result
Duration:
96 h
Dose descriptor:
LC50
Effect conc.:
> 100 mg/L
Nominal / measured:
nominal
Basis for effect:
mortality (fish)
Duration:
72 h
Dose descriptor:
LC50
Effect conc.:
> 100 mg/L
Nominal / measured:
nominal
Basis for effect:
mortality (fish)
Duration:
48 h
Dose descriptor:
LC50
Effect conc.:
> 100 mg/L
Nominal / measured:
nominal
Basis for effect:
mortality (fish)
Duration:
24 h
Dose descriptor:
LC50
Effect conc.:
> 100 mg/L
Nominal / measured:
nominal
Basis for effect:
mortality (fish)
Details on results:
%Concentration loss over test: 0
Conclusions:
No mortalities or sublethal effects were seen
Executive summary:

Study was performed according to OECD 203 guidance under GLP condition as a limit test. The total duration of the test was 96 hours. The test with Oncorhynchus mykiss (previous name: Salmo gairdneri) was performed under static condition. The measured test concertation over the first and last 24 hours of the exposure period were 101 - 89.4 mg/l and 105 - 104 mg/l respectively. During whole testing period no mortalities or sublethal effects were seen. The LC 50 based on fish mortality was established as more than 100mg/L. The NOEC (no observed effect concertation) was established as 100 mg/L (based on fish mortality).

Description of key information

Study was performed according to OECD 203 guidance under GLP condition as a limit test. The total duration of the test was 96 hours. The test with Oncorhynchus mykiss (previous name: Salmo gairdneri) was performed under static condition. The measured test concertation over the first and last 24 hours of the exposure period were 101 - 89.4 mg/l and 105 - 104 mg/l respectively. During whole testing period no mortalities or sublethal effects were seen. The LC 50 based on fish mortality was established as more than 100mg/L. The NOEC (no observed effect concertation) was established as 100 mg/L (based on fish mortality).

Key value for chemical safety assessment

Fresh water fish

Fresh water fish
Dose descriptor:
EC50
Effect concentration:
> 100 mg/L

Additional information