Registration Dossier

Diss Factsheets

Toxicological information

Acute Toxicity: oral

Currently viewing:

Administrative data

Endpoint:
acute toxicity: oral
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Original Report not available.

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1976

Materials and methods

Test guideline
Guideline:
other: no data
GLP compliance:
no
Test type:
acute toxic class method

Test material

Constituent 1
Chemical structure
Reference substance name:
5-chloro-o-toluidine
EC Number:
202-452-6
EC Name:
5-chloro-o-toluidine
Cas Number:
95-79-4
Molecular formula:
C7H8ClN
IUPAC Name:
5-chloro-2-methylaniline

Test animals

Species:
rat
Strain:
Wistar
Sex:
male/female

Administration / exposure

Route of administration:
oral: gavage
Vehicle:
other: sesame oil

Results and discussion

Effect levelsopen allclose all
Sex:
female
Dose descriptor:
LD50
Effect level:
716 mg/kg bw
Based on:
test mat.
95% CL:
>= 646 - <= 793
Sex:
male
Dose descriptor:
LD50
Effect level:
632 mg/kg bw
Based on:
test mat.
95% CL:
>= 551 - <= 726

Applicant's summary and conclusion

Categories Display