Registration Dossier
Registration Dossier
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Reaction mass of 2-{[3-(trimethoxysilyl)propyl]amino}ethanaminium chloride and 2-{benzyl[3-(trimethoxysilyl)propyl]amino}ethanaminium chloride and N-[2-(benzylamino)ethyl]-3-(trimethoxysilyl)propan-1-aminium chloride and N-[2-(dibenzylamino)ethyl]-3-(trimethoxysilyl)propan-1-aminium chloride and N-benzyl-2-{benzyl[3-(trimethoxysilyl)propyl]amino}ethanaminium chloride and N-benzyl-N-[2-(dibenzylamino)ethyl]-3-(trimethoxysilyl)propan-1-aminium chloride.
EC number: 700-961-2 | CAS number: -
Long-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
NOEC (28 d) = 5 mg/L (nominal, OECD 215)
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Effect concentration:
- 5 mg/L
Additional information
The study (2004) testing the long term toxicity of reaction mass containing six benzylated amine silanes to fish was conducted according to OECD guidance 215 using Oncorhynchus mykiss as the test organism. The test item degrades fast in water into oligomeric and polymeric silicon compounds and methanol. According to the OECD Guidance Document on Aquatic Toxicity Testing of Difficult Substances and Mixtures, substances which hydrolyse and form polymers, a flow through exposure system is not considered appropriate. Therefore, for the long term test a semi-static test design with a test medium renewal of three times per week was chosen. Since reaction mass containing six benzylated amine silanes reacts immediately with water, the biological results are based on the nominal concentrations of the test item. In the 28 day juvenile growth test, rainbow trout was exposed to nominal test item concentrations of 0.5, 1.6, 5, 16 and 50 mg/L. The highest concentration tested without toxic effects (NOEC) was determined to be 5.0 mg/L (nominal). The lowest concentration tested with toxic effects (LOEC) amounted 16 mg/L due to the statistically significantly reduced growth of the test fish at this test concentration. It is assumed that the test organisms were primarily exposed to the hydrolysis products of the substance.
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