Registration Dossier

Diss Factsheets

Administrative data

Endpoint:
melting point/freezing point
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: Study conducted in accordance with EU and OECD guidelines and to GLP.

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2010
Report date:
2010

Materials and methods

Test guidelineopen allclose all
Qualifier:
according to guideline
Guideline:
OECD Guideline 102 (Melting point / Melting Range)
Qualifier:
according to guideline
Guideline:
EU Method A.1 (Melting / Freezing Temperature)
GLP compliance:
yes (incl. QA statement)
Type of method:
capillary method

Test material

Constituent 1
Chemical structure
Reference substance name:
Propazine
EC Number:
205-359-9
EC Name:
Propazine
Cas Number:
139-40-2
Molecular formula:
C9H16ClN5
IUPAC Name:
6-chloro-N2,N4-bis(propan-2-yl)-1,3,5-triazine-2,4-diamine
Details on test material:
- Name of test material (as cited in study report): Propazine
- Molecular formula (if other than submission substance):
- Molecular weight (if other than submission substance):
- Smiles notation (if other than submission substance):
- InChl (if other than submission substance):
- Structural formula attached as image file (if other than submission substance): see Fig.
- Substance type:
- Physical state: Solid
- Analytical purity: 98.4%
- Impurities (identity and concentrations):
- Composition of test material, percentage of components:
- Isomers composition:
- Purity test date:
- Lot/batch No.: 09230119
- Expiration date of the lot/batch: 27 October 2014
- Radiochemical purity (if radiolabelling):
- Specific activity (if radiolabelling):
- Locations of the label (if radiolabelling):
- Expiration date of radiochemical substance (if radiolabelling):
- Stability under test conditions:
- Storage condition of test material: Room temperature in the dark
- Other:

Results and discussion

Melting / freezing point
Melting / freezing pt.:
192.5 - <= 216 °C
Decomposition:
ambiguous
Remarks:
The molten test substance was observed to be faintly yellow in appearance, indicating possible onset of decomposition.

Applicant's summary and conclusion

Conclusions:
The melting point of promazine at atmospheric pressure was found to be between 192.5 and 216 °C.
Executive summary:

The melting point of promazine at atmospheric pressure was found to be between 192.5 and 216 °C.