Propazine

Boiling point

Administrative data

Endpoint:

boiling point

Type of information:

experimental study

Adequacy of study:

key study

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

other: Study conducted to EU and OECD guidelines and to GLP.

Data source

Reference

Reference Type:

study report

Title:

Unnamed

Year:

2010

Report date:

2010

Materials and methods

Test guideline

Test guideline 1

Qualifier:

according to guideline

Guideline:

EU Method A.2 (Boiling Temperature)

Test guideline 2

Qualifier:

according to guideline

Guideline:

OECD Guideline 103 (Boiling point/boiling range)

GLP compliance:

yes (incl. QA statement)

Test material

Test material information

Constituent 1

Reference substance name:

Propazine

EC Number:

205-359-9

EC Name:

Propazine

Cas Number:

139-40-2

Molecular formula:

C9H16ClN5

IUPAC Name:

6-chloro-N2,N4-bis(propan-2-yl)-1,3,5-triazine-2,4-diamine

Details on test material:

- Name of test material (as cited in study report): Propazine
- Molecular formula (if other than submission substance):
- Molecular weight (if other than submission substance):
- Smiles notation (if other than submission substance):
- InChl (if other than submission substance):
- Structural formula attached as image file (if other than submission substance): see Fig.
- Substance type:
- Physical state: Solid
- Analytical purity: 98.4%
- Impurities (identity and concentrations):
- Composition of test material, percentage of components:
- Isomers composition:
- Purity test date: 23/11/2009
- Lot/batch No.: 09230119
- Expiration date of the lot/batch: 27/10/2014
- Radiochemical purity (if radiolabelling):
- Specific activity (if radiolabelling):
- Locations of the label (if radiolabelling):
- Expiration date of radiochemical substance (if radiolabelling):
- Stability under test conditions:
- Storage condition of test material: Room temperature in the dark
- Other:

Results and discussion

Boiling point

Atm. press.:

1 008 mBar

Decomposition:

yes

Remarks on result:

other: The boiling temperature of Propazine was not determinable, as the test substance decomposed on melting.

Any other information on results incl. tables

It was noted during the melting point determination that the test substance formed a faintly yellow melt, indicating possible onset of decomposition. In the course of the boiling point determination (both in a preliminary test at 10ºC/minute, and a subsequent test at 1ºC/minute) the test substance continued to darken after melting. Additionally, in the test at 1ºC/minute, evolution of gas was noted from the sample at approximately 230ºC and this resulted in the sample being forced up the boiling tube at approximately 240ºC. These observations confirmed that the test substance decomposed on melting.

Applicant's summary and conclusion

Conclusions:

The boiling temperature of Propazine was not determinable, as the test substance decomposed on melting.

Executive summary:

The boiling temperature of Propazine was not determinable, as the test substance decomposed on melting.