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Administrative data

Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
Study period:
from 13 November 1987 to 20 November 1987
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: GLP study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1987
Report date:
1987

Materials and methods

Test guidelineopen allclose all
Qualifier:
according to guideline
Guideline:
OECD Guideline 107 (Partition Coefficient (n-octanol / water), Shake Flask Method)
Deviations:
not specified
Qualifier:
according to guideline
Guideline:
EU Method A.8 (Partition Coefficient)
Deviations:
not specified
GLP compliance:
yes
Type of method:
shake-flask method to: flask method
Partition coefficient type:
octanol-water

Test material

Constituent 1
Chemical structure
Reference substance name:
Propazine
EC Number:
205-359-9
EC Name:
Propazine
Cas Number:
139-40-2
Molecular formula:
C9H16ClN5
IUPAC Name:
6-chloro-N2,N4-bis(propan-2-yl)-1,3,5-triazine-2,4-diamine
Details on test material:
Product designation: Propazine
Batch: 129/103
Molecolar weight: 229.7

Study design

Analytical method:
other: Spectrophotometry

Results and discussion

Partition coefficient
Type:
log Pow
Partition coefficient:
3.01
Temp.:
25 °C
pH:
7.1
Details on results:
The value of the partition coefficient n-octanol/water is the mean value of 6 determinations.

Any other information on results incl. tables

It has been evaluated also the partition coefficient of the substance by the fragment method of C. Hansch and A. Leo, CLOGP 3.4. The value obtained via such methos was : log Pow, cal = 3.13

Applicant's summary and conclusion