Registration Dossier

Administrative data

Description of key information

Di-2 -EHTDG is not toxic via the oral and dermal route. The LD50 values are greater than 5000 and 2000 mg/kg bw, respectively.
Inhalation is not a relevant route of exposure because of the low vapour pressure and the lack of inhalation exposure via aerosols.

Key value for chemical safety assessment

Acute toxicity: via oral route

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed
Dose descriptor:
discriminating dose
Value:
5 000 mg/kg bw

Acute toxicity: via inhalation route

Endpoint conclusion
Endpoint conclusion:
no study available

Acute toxicity: via dermal route

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed
Dose descriptor:
discriminating dose
Value:
2 000 mg/kg bw

Additional information

Di-2 -EHTDG is not toxic via the oral and dermal route.the LD50 values are greater than 5000 and 2000 mg/kg bw, respectively.

Inhalation is not a relevant route of exposure because of the low vapour pressure (0.0001 Pa at 25 °C) and the lack of inhalation exposure via aerosols.


Justification for selection of acute toxicity – oral endpoint
Di-2 -EHTDG is not toxic via the oral route. The LD50 values are greater than 5000 mg/kg bw.

Justification for selection of acute toxicity – inhalation endpoint
Inhalation is not a relevant route of exposure because of the low vapour pressure and the lack of inhalation exposure via aerosols.

Justification for selection of acute toxicity – dermal endpoint
Di-2 -EHTDG is not toxic via the dermal route. The LD50 values are greater than 2000 mg/kg bw.

Justification for classification or non-classification

The criteria for classification (LD50 < 2000 mg/kg bw) are not reached.