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Diss Factsheets

Ecotoxicological information

Long-term toxicity to fish

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Administrative data

Endpoint:
fish early-life stage toxicity
Type of information:
experimental study planned (based on read-across)
Remarks:
ECHA decision on testing proposal TPE-D-2114577079-36-01/F
Justification for type of information:
- Name of the substance on which testing is proposed to be carried out: sodium tellurite (IV)
- Name of the substance for which the testing proposal will be used: tellurium dioxide
Tellurium dioxide is relatively poorly water soluble. Underlying the basic assumption that effects caused by the bioavailable metal fraction and the same toxicokinetic behaviour, ecotoxicity data from higher soluble tellurium compound were considered appropriate for the ecotoxicity assessment of tellurium.
Based on the results of a transformation dissolution screening and determination of the dissolved element concentrations, we may conclude that dissolved tellurium dioxide is predominantly available as Te(IV). Sodium tellurite (IV) is therefore considered an adequate testing material for OECD 210 and for read-across to tellurium dioxide.
Cross-reference
Reason / purpose for cross-reference:
read-across: supporting information
Reference
Endpoint:
additional information on environmental fate and behaviour
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2022
Reliability:
1 (reliable without restriction)
Qualifier:
according to guideline
Guideline:
other: OECD 29 Guidance Document on Transformation/Dissolution of Metals and Metal Compounds in Aqueous Media.
Version / remarks:
July 2001
GLP compliance:
yes
Specific details on test material used for the study:
sodium tellurate (VI) and sodium tellurite (IV) have been used as standards to identify dissolved tellurium species

For the test at nominal pH 6 at a loading of 100 mg/L Tellurium dioxide, average dissolved concentrations of:
• 0.383 ± 0.125 mg/L Tetotal (CVoverall = 33 %; N = 9),
• 0.389 ± 0.129 mg/L Te(IV) (CVoverall = 33 %; N = 9),
• <0.002 mg/L Te(VI) (N = 9),
were found at the 24 hours endpoint.
Based on the tellurium content in the test item and the average dissolved concentrations in the test solutions:
• a release of tellurium of 0.48 % of the content,
• a release of tellurium(IV) of 0.49 % of the content,
• a release of tellurium(VI) of <0.003 % of the content,
could be calculated at the 24 hours endpoint in test medium at pH 6.
For the test at nominal pH 8 at a loading of 100 mg/L Tellurium dioxide, average dissolved concentrations of:


• 1.80 ± 0.23 mg/L Tetotal (CVoverall = 13 %; N = 9),
• 1.79 ± 0.24 mg/L Te(IV) (CVoverall = 13 %; N = 9),
• 0.002 ± 0.001 mg/L Te(VI) (CVoverall = 24 %; N = 9),
were found at the 24 hours endpoint.
Based on the tellurium content in the test item and the average dissolved concentrations in the test solutions:
• a release of tellurium of 2.3 % of the content,
• a release of tellurium(IV) of 2.2 % of the content,
• a release of tellurium(VI) of 0.003 % of the content,
could be calculated at the 24 hours endpoint in test medium at pH 8.

Conclusions:
During this study on Tellurium dioxide at a loading of 100 mg/L, it was shown that:
• For total tellurium, an average concentration of 0.383 mg/L Tetotal (CVoverall = 33 %; N = 9) was measured at pH 6 (i.e. 0.48 % total tellurium release) and 1.80 mg/L Tetotal (CVoverall = 13 %; N = 9) at pH 8 (i.e. 2.3 % total tellurium release),
• For tellurium(IV), an average concentration of 0.389 mg/L Te(IV) (CVoverall = 33 %; N = 9) was measured at pH 6 (i.e. 0.49 % tellurium(IV) release) and 1.79 mg/L Te(IV) (CVoverall = 13 %; N = 9) at pH 8 (i.e. 2.2 % tellurium(IV) release),
• For tellurium(VI), an average concentration of <0.002 mg/L Te(VI) (N = 9) was measured at pH 6 (i.e. <0.003 % tellurium(VI) release) and 0.002 mg/L Te(VI) (CVoverall = 24 %; N = 9) at pH 8 (i.e. 0.003 % tellurium(VI) release),
after 24 hours of exposure to the test medium at pH 6 and 8, respectively.
Based on the rounded results of the dissolved element concentrations, we may conclude that nominal “pH 8” is the pH where the highest dissolved tellurium concentrations, available as Te(IV), were measured. Only traces of Te(VI) could be detected.

Data source

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
OECD Guideline 210 (Fish, Early-Life Stage Toxicity Test)

Test material

Constituent 1
Chemical structure
Reference substance name:
sodium tellurite
Cas Number:
10102-20-2
Molecular formula:
Na2O3Te
IUPAC Name:
sodium tellurite

Results and discussion

Applicant's summary and conclusion