Registration Dossier

Administrative data

Endpoint:
respiratory sensitisation
Remarks:
other: DEREK Nexus software
Type of information:
other: DEREK Nexus
Adequacy of study:
weight of evidence
Study period:
2012
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: not OECD method was used

Data source

Reference
Reference Type:
other: DEREK Nexus software
Title:
Unnamed
Year:
2012
Report date:
2012

Materials and methods

Test guideline
Qualifier:
no guideline followed
GLP compliance:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
(1S,3R,7S,8S,8aR)-8-{2-[(2R,4R)-4-hydroxy-6-oxotetrahydro-2H-pyran-2-yl]ethyl}-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl (2S)-2-methylbutanoate
EC Number:
616-212-7
Cas Number:
75330-75-5
Molecular formula:
C24-H36-O5
IUPAC Name:
(1S,3R,7S,8S,8aR)-8-{2-[(2R,4R)-4-hydroxy-6-oxotetrahydro-2H-pyran-2-yl]ethyl}-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl (2S)-2-methylbutanoate

Results and discussion

Applicant's summary and conclusion

Interpretation of results:
not sensitising
Conclusions:
Computational toxicology summary was prepared by DEREK Nexus version 2.0.2 software, and the result for respiratory sensitisation is negative.
Executive summary:

Computational toxicology summary was prepared by DEREK Nexus version 2.0.2 software, and the result for respiratory sensitisation is negative.