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Ecotoxicological information

Long-term toxicity to aquatic invertebrates

Administrative data

Endpoint:
long-term toxicity to aquatic invertebrates
Type of information:
experimental study
Adequacy of study:
other information
Study period:
03-05 August 2009
Reliability:
1 (reliable without restriction)

Data source

Materials and methods

Test guidelineopen allclose all
Qualifier:
according to guideline
Guideline:
other: OECD guidelines for Testing of Chemicals, guideline No. 202: "Daphnia sp., Acute Immobilisation Test", Adopted April 13, 2004.
Qualifier:
according to guideline
Guideline:
other: ISO International Standard 6341: "Water quality - Determination of the inhibition of the mobility of Daphnia magna Straus - Acute toxicity test, Third edition, 1996-04-01.
Qualifier:
according to guideline
Guideline:
other: Commission Regulation (EC) No 440/2008 of 30 May 2008, Part C: Methods for the determination of ecotoxicity, Publication No. L142, C.2. "Daphnia Sp. Acute Immobilisation Test".
Qualifier:
according to guideline
Guideline:
other: Guidance document on aquatic toxicity testing of difficult substances and mixtures, OECD series on testing and assessment number 23, December 14, 2000.
GLP compliance:
yes

Test material

Constituent 1
Chemical structure
Reference substance name:
2-cyano-N-(2,4-dichloro-5-methoxyphenyl)acetamide
EC Number:
617-590-6
Cas Number:
846023-24-3
Molecular formula:
C10H8Cl2N2O2
IUPAC Name:
2-cyano-N-(2,4-dichloro-5-methoxyphenyl)acetamide
Details on test material:
Description Ivory flakes (determined at NOTOX)
Batch 18238505
Purity 97.3%
Test substance storage: At room temperature in the dark

Test organisms

Test organisms (species):
Daphnia magna

Study design

Test type:
static
Water media type:
not specified
Total exposure duration:
48 h

Results and discussion

Effect concentrations
Duration:
48 h
Dose descriptor:
EC50
Effect conc.:
>= 13 mg/L

Applicant's summary and conclusion

Conclusions:
Under the conditions of the present study WAY-186478 did not induce acute immobilisation of Daphnia magna at an initial measured exposure concentration of 13 mg/l after 48 hours of exposure (NOEC).
The 48h-EC50 was beyond the range tested, i.e. exceeded an initial measured exposure concentration of 13 mg/l, which was considered the maximum soluble concentration in test medium.