Registration Dossier
Registration Dossier
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EC number: 617-590-6 | CAS number: 846023-24-3
Long-term toxicity to aquatic invertebrates
Administrative data
- Endpoint:
- long-term toxicity to aquatic invertebrates
- Type of information:
- experimental study
- Adequacy of study:
- other information
- Study period:
- 03-05 August 2009
- Reliability:
- 1 (reliable without restriction)
Data source
Materials and methods
Test guidelineopen allclose all
- Qualifier:
- according to guideline
- Guideline:
- other: OECD guidelines for Testing of Chemicals, guideline No. 202: "Daphnia sp., Acute Immobilisation Test", Adopted April 13, 2004.
- Qualifier:
- according to guideline
- Guideline:
- other: ISO International Standard 6341: "Water quality - Determination of the inhibition of the mobility of Daphnia magna Straus - Acute toxicity test, Third edition, 1996-04-01.
- Qualifier:
- according to guideline
- Guideline:
- other: Commission Regulation (EC) No 440/2008 of 30 May 2008, Part C: Methods for the determination of ecotoxicity, Publication No. L142, C.2. "Daphnia Sp. Acute Immobilisation Test".
- Qualifier:
- according to guideline
- Guideline:
- other: Guidance document on aquatic toxicity testing of difficult substances and mixtures, OECD series on testing and assessment number 23, December 14, 2000.
- GLP compliance:
- yes
Test material
- Reference substance name:
- 2-cyano-N-(2,4-dichloro-5-methoxyphenyl)acetamide
- EC Number:
- 617-590-6
- Cas Number:
- 846023-24-3
- Molecular formula:
- C10H8Cl2N2O2
- IUPAC Name:
- 2-cyano-N-(2,4-dichloro-5-methoxyphenyl)acetamide
- Details on test material:
- Description Ivory flakes (determined at NOTOX)
Batch 18238505
Purity 97.3%
Test substance storage: At room temperature in the dark
Constituent 1
Test organisms
- Test organisms (species):
- Daphnia magna
Study design
- Test type:
- static
- Water media type:
- not specified
- Total exposure duration:
- 48 h
Results and discussion
Effect concentrations
- Duration:
- 48 h
- Dose descriptor:
- EC50
- Effect conc.:
- >= 13 mg/L
Applicant's summary and conclusion
- Conclusions:
- Under the conditions of the present study WAY-186478 did not induce acute immobilisation of Daphnia magna at an initial measured exposure concentration of 13 mg/l after 48 hours of exposure (NOEC).
The 48h-EC50 was beyond the range tested, i.e. exceeded an initial measured exposure concentration of 13 mg/l, which was considered the maximum soluble concentration in test medium.
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