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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Description of key information

LD50, rat, oral > 300 < 2000 mg/kg bw (BASF SE, 2008)

Key value for chemical safety assessment

Additional information

Oral:

In the key study, that was performed according to OECD guideline 423 in compliance with GLP, single doses of 2000 and 300 mg/kg body weight of the test material Adamantyltrimethylammoniumhydroxid 20% or test material preparations in doubly distilled water were given to three test groups of three fasted female animals each, (2000 mg/kg bw in 3 females, 300 mg/kg bw in 6 females) by gavage in a sequential manner (BASF SE, 2008). Under the conditions of this study the LD50 of Adamantyltrimethylammoniumhydroxid 20% after oral administration was found to be greater than 300 mg/kg and less than 2000 mg/kg body weight in rats.

Dermal:

There are no data available concerning acute dermal toxicity.

Inhalation:

There are no data available concerning acute inhalation toxicity.

Justification for classification or non-classification

EU classification according to Annex VI of Directive 67/548/EEC:

- Oral route: Xn, R22

- Dermal route: no classification due to lacking data

- Inhalation route: no classification due to lacking data

GHS classification according to Annex I 1272/2008 CLP (EU GHS):

- Oral route: Acute toxicity Cat. 4; H302

- Dermal route: no classification due to lacking data

- Inhalation route: no classification due to lacking data