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EC number: 500-655-7 | CAS number: 161308-15-2
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Long-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
A study was conducted to determine the effects of the test substance on the reproductive capacity of Daphnia magna according to OECD Guideline 211 and OECD Guidance document 23. The reproduction test was done as a limit test based on the results of a preceding range-finding study. The reproduction test was performed in a semi-static system. The study duration was 21 d and the test solutions were renewed every 48 h. 3 out 20 parental daphnids in the control and 1 out of 20 daphnid died in the test group. On average, 92 offspring were produced per surviving daphnid in the control treatment whereas 101 offspring were counted on average in the treatment group. There was no delay in first reproduction in the test group in comparison to the control. There were a few insignificant recordings of immobile young and appearance of unhatched (aborted) eggs in the test group during the 21 -d test period. The mean body length of the parents exposed to the control and the test substance group were comparable. The concentrations measured in the freshly prepared test solutions ranged between 0.035 and 0.218 mg/L (average measured concentration of 0.068 mg/L) and were expected to be above the water solubility limit of the test substance (<0.025 mg/L). The study met the acceptability criteria prescribed by the study plan and was considered valid.Under the study conditions, the 21-d NOEC and EC10 of the test substance for reproduction in Daphnia magna was determined to be 0.068 mg/L (average measured concentration) (Migchielsen, 2017).
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 0.068 mg/L
Additional information
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