4,4'-Isopropylidenediphenol, oligomeric reaction products with 1-chloro-2,3-epoxypropane, reaction products with biphenyl-4-ol

Toxicity to aquatic algae and cyanobacteria

Description of key information

72h-EC50 is greater than 0.23 mg/L and 72h-NOEC is 0.23 mg/L. Due to the very low solubility of E-200 in water (< 0.025 mg/l), concentration levels that might be toxic for algae could not be reached.

Key value for chemical safety assessment

EC50 for freshwater algae:

0.23 mg/L

EC10 or NOEC for freshwater algae:

0.23 mg/L

Additional information

The algae growth inhibition test with the test substance was conducted accoring to OECD TG 201 with GLP, one control and a loading rate of 100 mg/L groups were applied. The actual test concentration in the sample taken from the WAF prepared at a loading rate of 100 mg/l was 0.72 mg/l at the start of the test and decreased to 0.13 mg/l after 24 hours of exposure. At the end of the test the measured concentration was 0.32 mg/l. Based on these results, the Time Weight Average concentration was 0.23 mg/l. The study met the acceptability criteria prescribed by the protocol and was considered valid. No reduction of growth rate or inhibition of yield was recorded at any of the concentrations of Epikote P tested.

Thus the EC50 for growth rate reduction (ERC50: 0-72h) and the EC50 for yield inhibition (EYC50: 0-72h) were both exceed a loading rate of 100 mg/l, corresponding to a TWA concentration of 0.23 mg/l. The NOEC for growth rate reduction and yield inhibition equalled a loading rate of 100 mg/l, corresponding to a TWA concentration of 0.23 mg/l. Due to the very low solubility of Epikote P in water (< 0.025 mg/l), concentration levels that might be toxic for algae could not be reached.